Counties with highest COVID-19 infection rates in Missouri

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July 1, 2022
Kbh3rd // Wikimedia Commons

Counties with highest COVID-19 infection rates in Missouri

The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.

Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely.

The United States as of Jun. 29 reached over 1 million COVID-19-related deaths and 87.3 million COVID-19 cases, according to Johns Hopkins University. Currently, 66.9% of the population is fully vaccinated, and 47.3% of vaccinated people have received booster doses.

Stacker compiled a list of the counties with highest COVID-19 infection rates in Missouri using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to Jun. 28, 2022. Cumulative cases per 100,000 served as a tiebreaker.

Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.

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#50. Sullivan County, MO

- New cases per 100k in the past week: 148 (9 new cases, +12% change from previous week)
- Cumulative cases per 100k: 28,790 (1,753 total cases)
--- 18.1% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 378 (23 total deaths)
--- 11.8% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 43.6% (2,655 fully vaccinated)
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#49. St. Clair County, MO

- New cases per 100k in the past week: 149 (14 new cases, +8% change from previous week)
- Cumulative cases per 100k: 22,965 (2,158 total cases)
--- 5.8% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 394 (37 total deaths)
--- 16.6% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 34.7% (3,262 fully vaccinated)
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Nja1985, retouched by Kbh3rd // Wikimedia Commons

#48. Johnson County, MO

- New cases per 100k in the past week: 152 (82 new cases, +95% change from previous week)
- Cumulative cases per 100k: 23,218 (12,552 total cases)
--- 4.8% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 266 (144 total deaths)
--- 21.3% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 43.9% (23,711 fully vaccinated)
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#47. Laclede County, MO

- New cases per 100k in the past week: 154 (55 new cases, -17% change from previous week)
- Cumulative cases per 100k: 23,260 (8,309 total cases)
--- 4.6% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 501 (179 total deaths)
--- 48.2% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 38.0% (13,588 fully vaccinated)
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Semipaw // Wikimedia Commons

#46. Christian County, MO

- New cases per 100k in the past week: 157 (139 new cases, -10% change from previous week)
- Cumulative cases per 100k: 24,479 (21,687 total cases)
--- 0.4% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 301 (267 total deaths)
--- 10.9% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 46.4% (41,119 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#45. Iron County, MO

- New cases per 100k in the past week: 158 (16 new cases, +100% change from previous week)
- Cumulative cases per 100k: 22,183 (2,246 total cases)
--- 9.0% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 435 (44 total deaths)
--- 28.7% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 39.2% (3,971 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#44. Pike County, MO

- New cases per 100k in the past week: 158 (29 new cases, +12% change from previous week)
- Cumulative cases per 100k: 23,899 (4,374 total cases)
--- 2.0% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 350 (64 total deaths)
--- 3.6% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 37.8% (6,915 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#43. Ste. Genevieve County, MO

- New cases per 100k in the past week: 162 (29 new cases, -15% change from previous week)
- Cumulative cases per 100k: 21,521 (3,851 total cases)
--- 11.7% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 218 (39 total deaths)
--- 35.5% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 45.2% (8,093 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#42. Barry County, MO

- New cases per 100k in the past week: 165 (59 new cases, +90% change from previous week)
- Cumulative cases per 100k: 19,073 (6,826 total cases)
--- 21.8% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 400 (143 total deaths)
--- 18.3% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 44.9% (16,055 fully vaccinated)
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Brian Hunter // Wikimedia Commons

#41. Benton County, MO

- New cases per 100k in the past week: 165 (32 new cases, +68% change from previous week)
- Cumulative cases per 100k: 22,481 (4,371 total cases)
--- 7.8% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 555 (108 total deaths)
--- 64.2% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 48.4% (9,407 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#40. Montgomery County, MO

- New cases per 100k in the past week: 173 (20 new cases, +5% change from previous week)
- Cumulative cases per 100k: 22,578 (2,608 total cases)
--- 7.4% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 502 (58 total deaths)
--- 48.5% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 49.3% (5,695 fully vaccinated)
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#39. Cedar County, MO

- New cases per 100k in the past week: 174 (25 new cases, -14% change from previous week)
- Cumulative cases per 100k: 21,332 (3,061 total cases)
--- 12.5% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 397 (57 total deaths)
--- 17.5% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 32.2% (4,625 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#38. Dallas County, MO

- New cases per 100k in the past week: 178 (30 new cases, -12% change from previous week)
- Cumulative cases per 100k: 23,374 (3,945 total cases)
--- 4.1% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 433 (73 total deaths)
--- 28.1% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 35.4% (5,970 fully vaccinated)
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#37. Taney County, MO

- New cases per 100k in the past week: 179 (100 new cases, +1% change from previous week)
- Cumulative cases per 100k: 24,734 (13,833 total cases)
--- 1.5% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 415 (232 total deaths)
--- 22.8% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 40.9% (22,888 fully vaccinated)
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Katherine Dowler // Wikimedia

#36. Cole County, MO

- New cases per 100k in the past week: 180 (138 new cases, +16% change from previous week)
- Cumulative cases per 100k: 27,070 (20,775 total cases)
--- 11.0% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 379 (291 total deaths)
--- 12.1% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 53.2% (40,822 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#35. Randolph County, MO

- New cases per 100k in the past week: 182 (45 new cases, +29% change from previous week)
- Cumulative cases per 100k: 25,137 (6,221 total cases)
--- 3.1% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 420 (104 total deaths)
--- 24.3% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 38.7% (9,568 fully vaccinated)
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Americasroof // Wikimedia Commons

#34. Holt County, MO

- New cases per 100k in the past week: 182 (8 new cases, +167% change from previous week)
- Cumulative cases per 100k: 25,324 (1,115 total cases)
--- 3.9% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 681 (30 total deaths)
--- 101.5% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 42.6% (1,876 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#33. Franklin County, MO

- New cases per 100k in the past week: 182 (189 new cases, -2% change from previous week)
- Cumulative cases per 100k: 25,825 (26,849 total cases)
--- 5.9% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 363 (377 total deaths)
--- 7.4% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 54.7% (56,865 fully vaccinated)
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#32. Perry County, MO

- New cases per 100k in the past week: 183 (35 new cases, +13% change from previous week)
- Cumulative cases per 100k: 27,200 (5,205 total cases)
--- 11.6% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 240 (46 total deaths)
--- 29.0% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 39.9% (7,633 fully vaccinated)
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#31. Marion County, MO

- New cases per 100k in the past week: 189 (54 new cases, +80% change from previous week)
- Cumulative cases per 100k: 29,026 (8,281 total cases)
--- 19.1% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 424 (121 total deaths)
--- 25.4% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 42.5% (12,119 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#30. Pulaski County, MO

- New cases per 100k in the past week: 194 (102 new cases, +89% change from previous week)
- Cumulative cases per 100k: 17,635 (9,277 total cases)
--- 27.7% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 221 (116 total deaths)
--- 34.6% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 51.8% (27,264 fully vaccinated)
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pasa47 // Wikimedia Commons

#29. Lincoln County, MO

- New cases per 100k in the past week: 198 (117 new cases, +23% change from previous week)
- Cumulative cases per 100k: 26,560 (15,674 total cases)
--- 8.9% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 237 (140 total deaths)
--- 29.9% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 39.5% (23,302 fully vaccinated)
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Onegentlemanofverona // Wikimedia Commons

#28. Callaway County, MO

- New cases per 100k in the past week: 199 (89 new cases, +46% change from previous week)
- Cumulative cases per 100k: 27,841 (12,457 total cases)
--- 14.2% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 297 (133 total deaths)
--- 12.1% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 47.8% (21,399 fully vaccinated)
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Canva

#27. Knox County, MO

- New cases per 100k in the past week: 202 (8 new cases, +14% change from previous week)
- Cumulative cases per 100k: 25,941 (1,027 total cases)
--- 6.4% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 354 (14 total deaths)
--- 4.7% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 40.1% (1,589 fully vaccinated)
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#26. St. Francois County, MO

- New cases per 100k in the past week: 202 (136 new cases, +53% change from previous week)
- Cumulative cases per 100k: 29,177 (19,611 total cases)
--- 19.7% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 445 (299 total deaths)
--- 31.7% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 44.0% (29,566 fully vaccinated)
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Andrew.Belair // Wikimedia Commons

#25. Adair County, MO

- New cases per 100k in the past week: 205 (52 new cases, -13% change from previous week)
- Cumulative cases per 100k: 22,681 (5,748 total cases)
--- 7.0% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 264 (67 total deaths)
--- 21.9% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 46.2% (11,713 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#24. Hickory County, MO

- New cases per 100k in the past week: 210 (20 new cases, +54% change from previous week)
- Cumulative cases per 100k: 19,950 (1,904 total cases)
--- 18.2% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 587 (56 total deaths)
--- 73.7% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 38.5% (3,674 fully vaccinated)
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Pixabay

#23. Boone County, MO

- New cases per 100k in the past week: 210 (379 new cases, +25% change from previous week)
- Cumulative cases per 100k: 25,390 (45,820 total cases)
--- 4.1% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 143 (258 total deaths)
--- 57.7% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 62.5% (112,832 fully vaccinated)
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JERRYE & ROY KLOTZ MD // Wikimedia Commons

#22. Macon County, MO

- New cases per 100k in the past week: 212 (32 new cases, +88% change from previous week)
- Cumulative cases per 100k: 24,820 (3,752 total cases)
--- 1.8% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 390 (59 total deaths)
--- 15.4% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 40.9% (6,188 fully vaccinated)
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Dazspell // Wikimedia Commons

#21. Scott County, MO

- New cases per 100k in the past week: 212 (81 new cases, +45% change from previous week)
- Cumulative cases per 100k: 29,702 (11,370 total cases)
--- 21.8% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 423 (162 total deaths)
--- 25.1% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 43.9% (16,818 fully vaccinated)
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Rob Neville Photos // Shutterstock

#20. St. Charles County, MO

- New cases per 100k in the past week: 215 (864 new cases, -13% change from previous week)
- Cumulative cases per 100k: 25,130 (101,028 total cases)
--- 3.1% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 235 (946 total deaths)
--- 30.5% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 61.9% (248,734 fully vaccinated)
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Canva

#19. Jefferson County, MO

- New cases per 100k in the past week: 218 (490 new cases, +4% change from previous week)
- Cumulative cases per 100k: 25,394 (57,156 total cases)
--- 4.2% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 294 (662 total deaths)
--- 13.0% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 45.3% (101,924 fully vaccinated)
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Jose Kevo // Wikicommons

#18. Greene County, MO

- New cases per 100k in the past week: 220 (644 new cases, +25% change from previous week)
- Cumulative cases per 100k: 24,957 (73,146 total cases)
--- 2.4% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 356 (1,044 total deaths)
--- 5.3% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 49.8% (145,870 fully vaccinated)
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Peek Creative Collective // Shutterstock

#17. Jasper County, MO

- New cases per 100k in the past week: 223 (270 new cases, +4% change from previous week)
- Cumulative cases per 100k: 29,434 (35,712 total cases)
--- 20.7% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 448 (543 total deaths)
--- 32.5% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 47.8% (57,989 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#16. Phelps County, MO

- New cases per 100k in the past week: 224 (100 new cases, +25% change from previous week)
- Cumulative cases per 100k: 23,938 (10,670 total cases)
--- 1.8% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 552 (246 total deaths)
--- 63.3% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 44.2% (19,714 fully vaccinated)
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#15. Buchanan County, MO

- New cases per 100k in the past week: 225 (197 new cases, +52% change from previous week)
- Cumulative cases per 100k: 28,656 (25,035 total cases)
--- 17.5% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 367 (321 total deaths)
--- 8.6% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 39.1% (34,126 fully vaccinated)
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Nyttend // Wikimedia Commons

#14. Lewis County, MO

- New cases per 100k in the past week: 225 (22 new cases, +144% change from previous week)
- Cumulative cases per 100k: 29,399 (2,874 total cases)
--- 20.6% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 440 (43 total deaths)
--- 30.2% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 34.4% (3,362 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#13. Linn County, MO

- New cases per 100k in the past week: 227 (27 new cases, -21% change from previous week)
- Cumulative cases per 100k: 22,248 (2,652 total cases)
--- 8.7% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 545 (65 total deaths)
--- 61.2% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 46.6% (5,556 fully vaccinated)
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Sean Pavone // Shutterstock

#12. St. Louis city, MO

- New cases per 100k in the past week: 233 (700 new cases, -9% change from previous week)
- Cumulative cases per 100k: 20,778 (62,454 total cases)
--- 14.8% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 263 (791 total deaths)
--- 22.2% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 59.7% (179,521 fully vaccinated)
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Jatpainter1 // Wikimedia Commons

#11. Polk County, MO

- New cases per 100k in the past week: 246 (79 new cases, +10% change from previous week)
- Cumulative cases per 100k: 25,945 (8,341 total cases)
--- 6.4% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 336 (108 total deaths)
--- 0.6% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 39.2% (12,617 fully vaccinated)
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Jon Kraft // Shutterstock

#10. Jackson County, MO

- New cases per 100k in the past week: 246 (1,726 new cases, +29% change from previous week)
- Cumulative cases per 100k: 31,550 (221,797 total cases)
--- 29.4% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 365 (2,564 total deaths)
--- 8.0% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 58.0% (407,623 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#9. Putnam County, MO

- New cases per 100k in the past week: 256 (12 new cases, +200% change from previous week)
- Cumulative cases per 100k: 22,956 (1,078 total cases)
--- 5.8% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 532 (25 total deaths)
--- 57.4% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 34.5% (1,621 fully vaccinated)
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Art davis // Wikimedia Commons

#8. Vernon County, MO

- New cases per 100k in the past week: 263 (54 new cases, +145% change from previous week)
- Cumulative cases per 100k: 25,648 (5,274 total cases)
--- 5.2% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 530 (109 total deaths)
--- 56.8% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 35.5% (7,296 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#7. Wayne County, MO

- New cases per 100k in the past week: 272 (35 new cases, +775% change from previous week)
- Cumulative cases per 100k: 19,048 (2,452 total cases)
--- 21.9% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 419 (54 total deaths)
--- 24.0% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 36.6% (4,715 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#6. Grundy County, MO

- New cases per 100k in the past week: 274 (27 new cases, +80% change from previous week)
- Cumulative cases per 100k: 26,914 (2,651 total cases)
--- 10.4% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 701 (69 total deaths)
--- 107.4% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 36.0% (3,546 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#5. Shelby County, MO

- New cases per 100k in the past week: 304 (18 new cases, -5% change from previous week)
- Cumulative cases per 100k: 27,875 (1,653 total cases)
--- 14.3% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 253 (15 total deaths)
--- 25.1% less deaths per 100k residents than Missouri
- Population that is fully vaccinated: 47.3% (2,803 fully vaccinated)
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JERRYE AND ROY KLOTZ MD // Wikimedia Commons

#4. Atchison County, MO

- New cases per 100k in the past week: 331 (17 new cases, +183% change from previous week)
- Cumulative cases per 100k: 27,746 (1,427 total cases)
--- 13.8% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 447 (23 total deaths)
--- 32.2% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 56.5% (2,907 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#3. Barton County, MO

- New cases per 100k in the past week: 340 (40 new cases, +264% change from previous week)
- Cumulative cases per 100k: 25,030 (2,942 total cases)
--- 2.7% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 442 (52 total deaths)
--- 30.8% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 33.5% (3,938 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#2. St. Louis County, MO

- New cases per 100k in the past week: 372 (3,698 new cases, +113% change from previous week)
- Cumulative cases per 100k: 24,576 (244,331 total cases)
--- 0.8% more cases per 100k residents than Missouri
- Cumulative deaths per 100k: 340 (3,384 total deaths)
--- 0.6% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 64.9% (645,521 fully vaccinated)
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Kbh3rd // Wikimedia Commons

#1. Mercer County, MO

- New cases per 100k in the past week: 470 (17 new cases, +240% change from previous week)
- Cumulative cases per 100k: 20,376 (737 total cases)
--- 16.4% less cases per 100k residents than Missouri
- Cumulative deaths per 100k: 387 (14 total deaths)
--- 14.5% more deaths per 100k residents than Missouri
- Population that is fully vaccinated: 36.2% (1,310 fully vaccinated)

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