Best San Francisco 49ers fantasy performances so far this season

Every season in the NFL produces performances that feel less like a single game and more like statistical outliers — explosive outings where quarterbacks pile up passing yards, running backs break off long scoring runs, and receivers turn routine targets into multi-touchdown afternoons. These are the kinds of games that separate good fantasy weeks from historic ones.

Stacker compiled a ranking of the best San Francisco 49ers fantasy performances in the 2026 season using data from Stathead. The list includes the highest single-game fantasy scores by quarterbacks, running backs, wide receivers, and tight ends. Players are ranked based on standard fantasy scoring.

#5. Brock Purdy, October 11, 2026
- Stats: 189 Passing Yards, 2 Passing TDs, 1 Interceptions
- Game: SFO vs SEA, 32-29 Win
- Fantasy points: 16.16

#4. Brock Purdy, October 4, 2026
- Stats: 218 Passing Yards, 2 Passing TDs, 0 Interceptions, 29 Rushing Yards
- Game: SFO vs DEN, 24-14 Win
- Fantasy points: 19.62

#3. Brock Purdy, September 10, 2026
- Stats: 205 Passing Yards, 3 Passing TDs, 1 Interceptions, 29 Rushing Yards
- Game: SFO vs LAR, 27-7 Win
- Fantasy points: 21.1

#2. Brock Purdy, September 20, 2026
- Stats: 287 Passing Yards, 2 Passing TDs, 0 Interceptions, 30 Rushing Yards, 1 Rushing TDs
- Game: SFO vs MIA, 35-13 Win
- Fantasy points: 28.48

#1. Brock Purdy, September 27, 2026
- Stats: 297 Passing Yards, 4 Passing TDs, 0 Interceptions, 34 Rushing Yards
- Game: SFO vs ARI, 36-30 Win
- Fantasy points: 31.28

#5. Christian McCaffrey, September 10, 2026
- Stats: 68 Rushing Yards, 0 Rushing TDs, 20 Receiving Yards
- Game: SFO vs LAR, 27-7 Win
- Fantasy points: 8.8

#4. Christian McCaffrey, October 4, 2026
- Stats: 52 Rushing Yards, 1 Rushing TDs, 18 Receiving Yards
- Game: SFO vs DEN, 24-14 Win
- Fantasy points: 13.0

#3. Christian McCaffrey, October 11, 2026
- Stats: 68 Rushing Yards, 1 Rushing TDs, 15 Receiving Yards
- Game: SFO vs SEA, 32-29 Win
- Fantasy points: 14.3

#2. Christian McCaffrey, September 27, 2026
- Stats: 75 Rushing Yards, 1 Rushing TDs, 41 Receiving Yards
- Game: SFO vs ARI, 36-30 Win
- Fantasy points: 17.6

#1. Christian McCaffrey, September 20, 2026
- Stats: 23 Rushing Yards, 2 Rushing TDs, 43 Receiving Yards
- Game: SFO vs MIA, 35-13 Win
- Fantasy points: 18.6

#5. Demarcus Robinson, September 10, 2026
- Stats: 50 Receiving Yards, 1 Receiving TDs, 2 Receptions, 3 Targets
- Game: SFO vs LAR, 27-7 Win
- Fantasy points: 11.0

#4. Deebo Samuel, September 10, 2026
- Stats: 48 Receiving Yards, 1 Receiving TDs, 6 Receptions, 7 Targets
- Game: SFO vs LAR, 27-7 Win
- Fantasy points: 12.0

#3. Deebo Samuel, October 4, 2026
- Stats: 26 Receiving Yards, 1 Receiving TDs, 5 Receptions, 6 Targets
- Game: SFO vs DEN, 24-14 Win
- Fantasy points: 13.0

#2. Deebo Samuel, September 27, 2026
- Stats: 80 Receiving Yards, 1 Receiving TDs, 0 Receptions, 0 Targets
- Game: SFO vs ARI, 36-30 Win
- Fantasy points: 15.4

#1. Mike Evans, October 11, 2026
- Stats: 113 Receiving Yards, 1 Receiving TDs, 7 Receptions, 10 Targets
- Game: SFO vs SEA, 32-29 Win
- Fantasy points: 19.3

#5. Luke Farrell, September 10, 2026
- Stats: 19 Receiving Yards, 0 Receiving TDs, 2 Receptions, 2 Targets
- Game: SFO vs LAR, 27-7 Win
- Fantasy points: 1.9

#4. George Kittle, October 11, 2026
- Stats: 24 Receiving Yards, 0 Receiving TDs, 5 Receptions, 6 Targets
- Game: SFO vs SEA, 32-29 Win
- Fantasy points: 2.4

#3. George Kittle, October 4, 2026
- Stats: 70 Receiving Yards, 1 Receiving TDs, 4 Receptions, 6 Targets
- Game: SFO vs DEN, 24-14 Win
- Fantasy points: 13.0

#2. George Kittle, September 20, 2026
- Stats: 80 Receiving Yards, 1 Receiving TDs, 4 Receptions, 4 Targets
- Game: SFO vs MIA, 35-13 Win
- Fantasy points: 14.0

#1. George Kittle, September 27, 2026
- Stats: 82 Receiving Yards, 2 Receiving TDs, 6 Receptions, 7 Targets
- Game: SFO vs ARI, 36-30 Win
- Fantasy points: 20.2

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