Do you know your government acronyms?

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In its nearly 250-year history, the United States has not only grown as a country with an ever-growing number of agencies and departments—it's also amassed an array of acronyms, some more memorable than others.

From POTUS to SCOTUS, FDA to FOIA, the people, offices, and agencies that form the foundation of America bring dozens of abbreviations to our nation's vocabulary. Whether to make sense of government-speak or navigate the alphabet soup of the daily news cycle, it helps to have a general understanding of them to stay informed.

Using data from governmental websites, encyclopedias, and news sources, Stacker has gathered a list of relevant offices and agencies—with corresponding clues to test your knowledge. How many can you identify off the top of your head? Follow the clues to find out.

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USDA

In 1862 Abraham Lincoln signed the act that created this agency, which had a mandate "to acquire and to diffuse … information on subjects connected with agriculture in the most general and comprehensive sense of that word."

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United States Department of Agriculture

From aiding American farmers to overseeing food safety, the USDA has a broad range of responsibilities. The USDA also subsidizes the Food and Nutrition Service, the federal agency that administers food stamps. Congress is currently negotiating the 2018 farm bill, which sets a five-year budget for the department.

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Department of Defense

Now dubbed the "Department of War" under a presidential order issued in September 2025, the Department of Defense is in charge of supplying the military forces necessary to defend the U.S. and ensure its safety. Former television personality and Army National Guard officer Peter Hegseth leads the department as the current Secretary of War.

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Department of Homeland Security

Currently chaired by Kristi Noem, the Department of Homeland Security has more than 240,000 employees in more than 12 key offices and committees—including the Office of Intelligence and Analysis, U.S. Customs and Border Protection, the U.S. Coast Guard, and the U.S. Secret Service.

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ICE

This is the second largest law enforcement organization in the U.S. and is operated by the Department of Homeland Security.

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Immigration and Customs Enforcement

In charge of enforcing immigration and customs law, ICE has been plastered across news headlines in 2025 as President Donald Trump seeks to fulfill a mass deportation agenda. As part of these efforts, ICE has conducted a series of high-profile raids in cities like Los Angeles, Miami, New York City, and more, sparking widespread backlash.

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CBP

Part of the Department of Homeland Security, this agency is a culmination of organizations with responsibilities of protecting the U.S. at its borders and ports of entries.

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NSA

Officially created by President Harry S. Truman in 1952, this part of the American intelligence community has been one of the government's most secretive spy operations since the Cold War. It specializes in cryptology, the science of coding and decoding information.

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National Security Administration

The National Security Agency operates under the Department of Defense, using mass information gathering to obtain data. In 2012, leaked documents from Edward Snowden detailed a wide range of secretive activities by this agency, including those meant to gather data on American citizens.

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FBI

Created in 1908 by President Theodore Roosevelt and Attorney General Charles Bonaparte, this agency is one of the government's top law enforcement agencies. It also acts as an intelligence agency, reporting to both the attorney general and the director of national intelligence.

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Federal Bureau of Investigation

The Federal Bureau of Investigation is headed by Kash Patel  and operates 56 field offices throughout major U.S. cities, as well as 380 resident agencies in smaller cities. In 2018, a Department of Justice report put the agency's credibility into question for mishandling an investigation into Hillary Clinton in regard to classified documents stored on her email server.

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Central Intelligence Administration

John L. Ratcliffe is the current director of the Central Intelligence Agency.

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Department of Housing and Urban Development

The Department of Housing and Urban Development was created in 1965 by President Lyndon B. Johnson. It is currently headed by Secretary Scott Turner, a former NFL player and Texas state representative.

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HHS

This civilian department aims to protect the health of all Americans and provides essential human services.

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Department of Health and Human Services

The Department of Health and Human Services is charged with implementing Medicare and Medicaid, as well as overseeing the Food and Drug Association, Centers for Disease Control and Prevention, and the National Institutes of Health.

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DOJ

This department is in charge of upholding federal laws, preventing crime, and protecting the public against any type of safety threat. It's also in charge of the federal prison system.

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Department of Justice

The department administers law enforcement agencies such as the Drug Enforcement Agency; Bureau of Alcohol, Tobacco, and Firearms and Explosives; Federal Bureau of Investigation; and United States Marshals Service.

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EPA

This agency was established in 1970 to research, monitor, enforce, and set standards for environmental protection.

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Drug Enforcement Administration

Created by President Nixon in 1973, the DEA maintains its mission to enforce its classification of marijuana as a Schedule I drug, even though multiple states and Washington D.C. have voted to legalize it for both recreational and medical use in recent years.

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FAA

This division of the U.S. Department of Transportation is in charge of regulating civil aviation and U.S. commercial space transportation, maintaining and operating air traffic control and navigation systems for both civil and military aircraft, and developing and administering programs relating to aviation safety and the National Airspace System.

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Federal Aviation Administration

The Federal Aviation Administration was established by the Federal Aviation Act of 1958 and became a part of the Department of Transportation in 1967. 

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FDIC

This independent agency was created by Congress in 1933 to maintain stability and public confidence in the nation's financial system.

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Federal Deposit Insurance Corporation

The Federal Deposit Insurance Corporation was created in response to the thousands of bank failures that occurred in the 1920s and 1930s. It insures deposits up to $250,000 and is funded by deposit insurance and earnings on investments in U.S. Treasury securities paid by banks and other savings and loan institutions.

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FEC

This regulatory agency was created in 1975 to promote confidence and participation in the democratic process.

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FEMA

This agency located within the Department of Homeland Security is responsible for managing the federal government's response to natural and manmade disasters.

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Federal Emergency Management Administration

The Federal Emergency Management Agency was founded in 1979 under President Jimmy Carter. In 2003, the agency became part of the U.S. Department of Homeland Security and was tasked with helping to ensure that first responders were able to deal with weapons of mass destruction. 

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Freedom of Information Act

Congress enacted the Freedom of Information Act in 1967. It requires federal agencies to disclose any information requested under the act unless it falls under one of nine exemptions, such as personal privacy, national security, and law enforcement.

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IRS

This government agency is in charge of enforcing the Internal Revenue Code.

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Internal Revenue Service

President Abraham Lincoln and Congress created the position of Commissioner of Internal Revenue in 1862, enacting an income tax to cover war costs. Although it was repealed shortly after, the 16th Amendment gave Congress the authority to collect income tax in 1913. The bureau changed its name to the Internal Revenue Service in 1953.

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LOC

This is the nation's oldest federal cultural institution, and it serves as the research arm of Congress.

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OSHA

This agency develops and enforces government standards that protect worker safety at U.S. job sites.

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Occupational Safety and Health Administration

The Occupational Safety and Health Administration is headed by Loren Sweatt, deputy assistant secretary of Labor for Occupational Safety and Health. It is housed in the Department of Labor and answers to the secretary of labor. The Occupational Safety and Health Act of 1970 established the department, which offers certain protections to most private sector employers and their employees.

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PTO

This government agency has been around for more than 200 years, and is primarily responsible for trademark and patent applications.

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Patent and Trademark Office

The Patent and Trademark Office not only grants U.S. patents and registers trademarks, they also advise the president, secretary of commerce, and government agencies on intellectual property policy, protection, and enforcement.

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Reserve Officer Training Corps

Since World War II, the Reserve Officer Training Corps has been the biggest source of officers for the armed forces. Distinct ROTC programs exist for the army, navy, and air force.

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SSA

This independent federal agency provides income to people who are retired or have disabilities.

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Social Security Administration

The Social Security Administration is the result of the Social Security Act, which President Roosevelt signed in 1935. The program has a $12 billion budget and nearly 64,000 employees.

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TANF

This government program helps needy families get on their feet and become self-sufficient.

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TSA

This agency protects the nation's transportation networks from attack.

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Transportation Security Administration

The Transportation and Security Administration was founded in November 2001 in response to the September 11 terrorist attacks. Its nearly 60,000 employees sit under the Department of Homeland Security.

 

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INS/USCIS

This agency administers the country's immigration system.

 

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Immigration and Naturalization Service/United States Citizenship and Immigration Services

The United States Citizenship and Immigration Services is in charge of lawful immigration to the U.S. The agency is staffed by 19,000 government employees and contract workers. Created within the Department of Homeland Security, the USCIS succeeds the INS, which was abolished in 2003.

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United States Air Force

The United States Air Force is one of five branches of the military, headed by Chief of Staff David W. Allvin, who reports to Secretary of War Peter Hegseth. The Air Force was founded in 1907 as part of the Army, becoming independent in 1947 with the passage of the National Security Act.

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USAID

This federal agency is in charge of foreign assistance to countries that are faced with disaster, poverty, and fledgling democracies.

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United States Agency for International Development

The United States Agency for International Development was established in 1961 by President John F. Kennedy and offers assistance to developing countries. The agency has operations in more than 100 nations.

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USPS

This department delivers mail and packages to every address in the U.S., as well as its territories and military installations around the world.

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VA

This department provides patient care and federal benefits to veterans and their dependents.

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Department of Veterans Affairs

The Department of Veterans Affairs took shape in 1930, when President Harry S. Truman signed Executive Order 5398. The administration boasts around 1,600 health care facilities.

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VOA

This government-funded, international, multimedia broadcast service provides news updates in more than 40 languages across the world.

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Voice of America

Initially established in 1942 to counteract Nazi propaganda efforts, Voice of America now provides news, information, and cultural programming through traditional and digital media efforts.

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Bureau of Alcohol, Tobacco and Firearms

The Bureau of Alcohol, Tobacco, Firearms and Explosives has a staff of 5,113 employees, which includes 2,623 special agents, and its annual budget in 2017 was $1.258 billion.

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CFPB

This government agency supervises banks, lenders, credit reporting agencies, and debt collection companies.

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Consumer Financial Protection Bureau

The Consumer Financial Protection Bureauk supervises U.S. financial institutions; it also works with companies to make credit card, mortgage, and loan disclosures transparent for consumers. The bureau was created when the Dodd-Frank Wall Street Reform and Consumer Protection Act passed in 2010.

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CBO

This government office independently analyzes budgetary and economic issues to support Congress in their budgeting process.

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DOT

This agency is responsible for the nation's transportation systems and infrastructure.

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Department of Transportation

Congress established the Department of Transportation in 1966. It is currently led by Secretary of Transportation Sean Duffy.

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CDC

This governmental organization is in charge of public health efforts to prevent and control infectious diseases, environmental threats, and workplace hazards.

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Centers for Disease Control

The Centers for Disease Control was founded in 1946 and is part of the U.S. Department of Health and Human Services. 

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National Center for Education Statistics

The National Center for Education Statistics is part of the U.S. Department of Education and the Institute of Education Sciences.

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FHA

This agency provides mortgage insurance on loans made by government-approved lenders throughout the country.

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Federal Housing Administration

The Federal Housing Administration insures mortgages on single and multi-family homes, as well as manufactured homes and hospitals. Founded in 1932, it has insured 47.5 million properties since its inception, making it the largest insurer of mortgages.



 

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National Labor Relations Board

Employees who feel that their rights have been violated, or that their employer has engaged in unlawful behavior, can contact a regional office of the National Labor Relations Board. The board has five members appointed by the president and approved by the Senate; they act as a quasi-judicial body in deciding cases.

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NSC

This group meets and advises the president of the United States on national security and foreign policy matters.

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National Security Council

The National Security Council was established under President Harry S. Truman by the National Security Act of 1947. Chaired by the president, it regularly includes the vice president, secretary of state, secretary of the treasury, secretary of defense, and the assistant to the president.

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Secret Service

The United States Secret Service was founded at the end of the American Civil War to combat counterfeiting of U.S. currency. It not only focuses on physically guarding the people who hold the highest offices in the U.S., but also helps the Department of Homeland Security protect American citizens from harm.

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CPSC

This independent federal agency protects U.S. consumers from potentially harmful or dangerous products sold domestically.

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BLS

This group within the Department of Labor measures labor market activity, working conditions, and price changes in the economy.

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Bureau of Labor Statistics

The mission of the Bureau of Labor Statistics is to measure labor market activity, as well as analyze and disseminate information to help public and private decision-making. The department is headed by a commissioner appointed by the president, who oversees 2,400 employees—mainly economists and statisticians.

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USFA

This division of the Federal Emergency Management Agency is the lead agency for fire data collection, public fire education, fire research, and fire service training.

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United States Fire Administration

Congress passed the Federal Fire Prevention and Control Act in 1974, which created the United States Fire Administration. Its mission is to curtail fire-related deaths through data collection, public education, research, and training.

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National Cancer Institute

Congress passed the National Cancer Act of 1937 to support cancer research and establish the National Cancer Institute. Its director leads the organization's 3,500-person team, which has a mission to save lives from the disease by supporting research across the country.

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NASA

This independent federal agency is in charge of the nation's space program.

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National Aeronautics and Space Administration

The National Aeronautics and Space Administration is currently led by US Secretary of Transportation Sean Duffy, who leads a staff of more than 18,000 people charged with military aerospace research, development of space missions, and training of astronauts. NASA was created in 1958 in response to the Soviet Union's launch of its first satellite, Sputnik I.


 

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DARPA

This agency is in charge of creating cutting-edge technologies and capabilities for national security.