Best Indianapolis Colts fantasy performances of the last decade

Every season in the NFL produces performances that feel less like a single game and more like statistical outliers — explosive outings where quarterbacks pile up passing yards, running backs break off long scoring runs, and receivers turn routine targets into multi-touchdown afternoons. These are the kinds of games that separate good fantasy weeks from historic ones.

Stacker compiled a ranking of the best Indianapolis Colts fantasy performances from 2016 to 2025 using data from Stathead. The list includes the highest single-game fantasy scores by quarterbacks, running backs, wide receivers, and tight ends. Players are ranked based on standard fantasy scoring.

#10. Gardner Minshew II, October 22, 2023
- Stats: 305 Passing Yards, 2 Passing TDs, 1 Interceptions, 29 Rushing Yards, 2 Rushing TDs
- Game: IND vs CLE, 38-39 Loss
- Fantasy points: 27.10

#9. Jacoby Brissett, October 20, 2019
- Stats: 326 Passing Yards, 4 Passing TDs, 0 Interceptions
- Game: IND vs HOU, 30-23 Win
- Fantasy points: 27.64

#8. Jacoby Brissett, September 24, 2017
- Stats: 259 Passing Yards, 1 Passing TDs, 0 Interceptions, 14 Rushing Yards, 2 Rushing TDs
- Game: IND vs CLE, 31-28 Win
- Fantasy points: 27.76

#7. Andrew Luck, October 23, 2016
- Stats: 353 Passing Yards, 3 Passing TDs, 0 Interceptions, 17 Rushing Yards
- Game: IND vs TEN, 34-26 Win
- Fantasy points: 27.82

#6. Anthony Richardson, November 17, 2024
- Stats: 272 Passing Yards, 1 Passing TDs, 0 Interceptions, 32 Rushing Yards, 2 Rushing TDs
- Game: IND vs NYJ, 28-27 Win
- Fantasy points: 28.08

#5. Daniel Jones, September 7, 2025
- Stats: 272 Passing Yards, 1 Passing TDs, 0 Interceptions, 26 Rushing Yards, 2 Rushing TDs
- Game: IND vs MIA, 33-8 Win
- Fantasy points: 29.48

#4. Anthony Richardson, October 1, 2023
- Stats: 200 Passing Yards, 2 Passing TDs, 0 Interceptions, 56 Rushing Yards, 1 Rushing TDs
- Game: IND vs LAR, 23-29 (OT) Loss
- Fantasy points: 29.60

#3. Andrew Luck, December 5, 2016
- Stats: 278 Passing Yards, 4 Passing TDs, 0 Interceptions, 26 Rushing Yards
- Game: IND vs NYJ, 41-10 Win
- Fantasy points: 29.72

#2. Andrew Luck, September 11, 2016
- Stats: 385 Passing Yards, 4 Passing TDs, 0 Interceptions, 21 Rushing Yards
- Game: IND vs DET, 35-39 Loss
- Fantasy points: 35.50

#1. Andrew Luck, September 30, 2018
- Stats: 464 Passing Yards, 4 Passing TDs, 0 Interceptions, 11 Rushing Yards
- Game: IND vs HOU, 34-37 (OT) Loss
- Fantasy points: 35.66

#10. Jonathan Taylor, September 21, 2025
- Stats: 102 Rushing Yards, 3 Rushing TDs, 16 Receiving Yards
- Game: IND vs TEN, 41-20 Win
- Fantasy points: 29.8

#9. Marlon Mack, October 21, 2018
- Stats: 126 Rushing Yards, 1 Rushing TDs, 33 Receiving Yards, 1 Receiving TDs
- Game: IND vs BUF, 37-5 Win
- Fantasy points: 29.9

#8. Jonathan Taylor, October 19, 2025
- Stats: 94 Rushing Yards, 3 Rushing TDs, 38 Receiving Yards
- Game: IND vs LAC, 38-24 Win
- Fantasy points: 31.2

#7. Zack Moss, October 8, 2023
- Stats: 165 Rushing Yards, 2 Rushing TDs, 30 Receiving Yards
- Game: IND vs TEN, 23-16 Win
- Fantasy points: 31.5

#6. Jonathan Taylor, November 4, 2021
- Stats: 172 Rushing Yards, 2 Rushing TDs, 28 Receiving Yards
- Game: IND vs NYJ, 45-30 Win
- Fantasy points: 32.0

#5. Jonathan Taylor, October 26, 2025
- Stats: 153 Rushing Yards, 2 Rushing TDs, 21 Receiving Yards, 1 Receiving TDs
- Game: IND vs TEN, 38-14 Win
- Fantasy points: 35.4

#4. Jonathan Taylor, January 3, 2021
- Stats: 253 Rushing Yards, 2 Rushing TDs
- Game: IND vs JAX, 28-14 Win
- Fantasy points: 37.4

#3. Jonathan Taylor, December 22, 2024
- Stats: 218 Rushing Yards, 3 Rushing TDs
- Game: IND vs TEN, 38-30 Win
- Fantasy points: 39.8

#2. Jonathan Taylor, November 9, 2025
- Stats: 244 Rushing Yards, 3 Rushing TDs, 42 Receiving Yards
- Game: IND vs ATL, 31-25 (OT) Win
- Fantasy points: 46.6

#1. Jonathan Taylor, November 21, 2021
- Stats: 185 Rushing Yards, 4 Rushing TDs, 19 Receiving Yards, 1 Receiving TDs
- Game: IND vs BUF, 41-15 Win
- Fantasy points: 50.4

#10. Alec Pierce, December 22, 2025
- Stats: 86 Receiving Yards, 2 Receiving TDs, 4 Receptions, 4 Targets
- Game: IND vs SFO, 27-48 Loss
- Fantasy points: 20.6

#9. T.Y. Hilton, December 13, 2020
- Stats: 86 Receiving Yards, 2 Receiving TDs, 5 Receptions, 7 Targets
- Game: IND vs LVR, 44-27 Win
- Fantasy points: 20.6

#8. T.Y. Hilton, September 8, 2019
- Stats: 87 Receiving Yards, 2 Receiving TDs, 8 Receptions, 9 Targets
- Game: IND vs LAC, 24-30 (OT) Loss
- Fantasy points: 20.7

#7. T.Y. Hilton, September 24, 2017
- Stats: 153 Receiving Yards, 1 Receiving TDs, 7 Receptions, 9 Targets
- Game: IND vs CLE, 31-28 Win
- Fantasy points: 21.3

#6. Zach Pascal, October 20, 2019
- Stats: 106 Receiving Yards, 2 Receiving TDs, 6 Receptions, 7 Targets
- Game: IND vs HOU, 30-23 Win
- Fantasy points: 22.6

#5. T.Y. Hilton, October 9, 2016
- Stats: 171 Receiving Yards, 1 Receiving TDs, 10 Receptions, 11 Targets
- Game: IND vs CHI, 29-23 Win
- Fantasy points: 23.1

#4. T.Y. Hilton, September 25, 2016
- Stats: 174 Receiving Yards, 1 Receiving TDs, 8 Receptions, 11 Targets
- Game: IND vs SDG, 26-22 Win
- Fantasy points: 23.4

#3. Alec Pierce, January 4, 2026
- Stats: 132 Receiving Yards, 2 Receiving TDs, 4 Receptions, 7 Targets
- Game: IND vs HOU, 30-38 Loss
- Fantasy points: 25.2

#2. T.Y. Hilton, November 18, 2018
- Stats: 155 Receiving Yards, 2 Receiving TDs, 9 Receptions, 9 Targets
- Game: IND vs TEN, 38-10 Win
- Fantasy points: 27.5

#1. T.Y. Hilton, November 5, 2017
- Stats: 175 Receiving Yards, 2 Receiving TDs, 5 Receptions, 9 Targets
- Game: IND vs HOU, 20-14 Win
- Fantasy points: 29.5

#10. Jack Doyle, January 9, 2021
- Stats: 70 Receiving Yards, 1 Receiving TDs, 7 Receptions, 9 Targets
- Game: IND vs BUF, 24-27 Loss
- Fantasy points: 15.0

#9. Jack Doyle, September 11, 2016
- Stats: 35 Receiving Yards, 2 Receiving TDs, 3 Receptions, 4 Targets
- Game: IND vs DET, 35-39 Loss
- Fantasy points: 15.5

#8. Mo Alie-Cox, October 3, 2021
- Stats: 42 Receiving Yards, 2 Receiving TDs, 3 Receptions, 5 Targets
- Game: IND vs MIA, 27-17 Win
- Fantasy points: 16.2

#7. Eric Ebron, November 25, 2018
- Stats: 45 Receiving Yards, 2 Receiving TDs, 5 Receptions, 7 Targets
- Game: IND vs MIA, 27-24 Win
- Fantasy points: 16.5

#6. Trey Burton, October 18, 2020
- Stats: 58 Receiving Yards, 1 Receiving TDs, 4 Receptions, 5 Targets
- Game: IND vs CIN, 31-27 Win
- Fantasy points: 17.9

#5. Jack Doyle, October 29, 2017
- Stats: 121 Receiving Yards, 1 Receiving TDs, 12 Receptions, 14 Targets
- Game: IND vs CIN, 23-24 Loss
- Fantasy points: 18.1

#4. Mo Alie-Cox, October 2, 2022
- Stats: 85 Receiving Yards, 2 Receiving TDs, 6 Receptions, 6 Targets
- Game: IND vs TEN, 17-24 Loss
- Fantasy points: 20.5

#3. Eric Ebron, October 4, 2018
- Stats: 105 Receiving Yards, 2 Receiving TDs, 9 Receptions, 15 Targets
- Game: IND vs NWE, 24-38 Loss
- Fantasy points: 22.5

#2. Eric Ebron, November 11, 2018
- Stats: 69 Receiving Yards, 2 Receiving TDs, 3 Receptions, 3 Targets
- Game: IND vs JAX, 29-26 Win
- Fantasy points: 25.1

#1. Dwayne Allen, December 5, 2016
- Stats: 72 Receiving Yards, 3 Receiving TDs, 4 Receptions, 4 Targets
- Game: IND vs NYJ, 41-10 Win
- Fantasy points: 25.2

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