Counties where the most opioids are dispensed in South Dakota

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When Purdue Pharma first began sales of OxyContin in the late 1990s, it was advertised as relief for cancer patients and people with chronic pain. Aggressive marketing fueled the drug's popularity, along with that of other opioid pain management drugs on the market. But as the company touted OxyContin to physicians, it downplayed the drug's addictiveness, according to confidential Justice Department reports obtained by news organizations, leading to widespread use that has fueled an opioid epidemic across the U.S.

More than 645,000 people have died from opioid-related overdoses between 1999 and 2021, according to the Centers for Disease Control and Prevention. Provisional data shows just under 80,000 people died in 2022 alone.

Opioid prescriptions have decreased dramatically over the past decade as physicians and public health officials learned about the dangers of OxyContin and other opioids prescribed for pain management. In 2020, the most recent year with data available, the national opioid dispense rate reached 43.3 per 100 people, the lowest rate ever recorded.

A 2022 study funded by the National Institute on Drug Abuse found that counties with higher dispensing rates had more cases of opioid misuse and dependence. The study suggested that reducing prescriptions at the local level can lower a community's rate of opioid abuse or misuse.

Other studies, however, have suggested that decreasing prescriptions may have fueled a new phase of the opioid epidemic: the rise of synthetics like fentanyl. In 2020, synthetics accounted for 82% of all opioid deaths.

It's also important to note that, as awareness has grown about the dangers of dispensing opioid prescription painkillers, more health care professionals are also prescribing medications like Suboxone–which contains buprenorphine and naloxone—for the treatment of addiction and opioid use disorders. While Suboxone is also an opioid medication, it works differently than typical opioid painkillers, blocking the effects of more powerful and addictive opioids to deter intentional misuse.

Using data from the Centers for Disease Control and Prevention, Ophelia broke down counties in every state with the highest opioid dispense rates. In the case of a tie, the county with the higher population and higher raw number is ranked higher. Data was available for 98% of counties in the United States. Overall in South Dakota, the opioid dispensing rate was 39.9 per 100 people, compared to 43.3 nationally.

Read the national story for additional historical context and see where other counties outside of South Dakota stand.

#50. Day County

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#50. Day County

- Opioid dispensing rate: 4.0 per 100 people
--- 90.0% lower than state average
--- 90.8% lower than national average

#49. Mcpherson County

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#49. Mcpherson County

- Opioid dispensing rate: 4.4 per 100 people
--- 89.0% lower than state average
--- 89.8% lower than national average

#48. Potter County

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#48. Potter County

- Opioid dispensing rate: 4.5 per 100 people
--- 88.7% lower than state average
--- 89.6% lower than national average

#47. Corson County

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#47. Corson County

- Opioid dispensing rate: 4.6 per 100 people
--- 88.5% lower than state average
--- 89.4% lower than national average

#46. Campbell County

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#46. Campbell County

- Opioid dispensing rate: 5.6 per 100 people
--- 86.0% lower than state average
--- 87.1% lower than national average

#45. Butte County

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#45. Butte County

- Opioid dispensing rate: 6.0 per 100 people
--- 85.0% lower than state average
--- 86.1% lower than national average

#44. Meade County

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#44. Meade County

- Opioid dispensing rate: 6.9 per 100 people
--- 82.7% lower than state average
--- 84.1% lower than national average

#43. Todd County

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#43. Todd County

- Opioid dispensing rate: 7.4 per 100 people
--- 81.5% lower than state average
--- 82.9% lower than national average

#42. Spink County

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#42. Spink County

- Opioid dispensing rate: 7.9 per 100 people
--- 80.2% lower than state average
--- 81.8% lower than national average

#41. Jackson County

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#41. Jackson County

- Opioid dispensing rate: 8.8 per 100 people
--- 77.9% lower than state average
--- 79.7% lower than national average

#40. Turner County

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#40. Turner County

- Opioid dispensing rate: 11.7 per 100 people
--- 70.7% lower than state average
--- 73.0% lower than national average

#39. Bon Homme County

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#39. Bon Homme County

- Opioid dispensing rate: 12.6 per 100 people
--- 68.4% lower than state average
--- 70.9% lower than national average

#38. Marshall County

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#38. Marshall County

- Opioid dispensing rate: 13.8 per 100 people
--- 65.4% lower than state average
--- 68.1% lower than national average

#37. Moody County

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#37. Moody County

- Opioid dispensing rate: 14.6 per 100 people
--- 63.4% lower than state average
--- 66.3% lower than national average

#36. Clark County

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#36. Clark County

- Opioid dispensing rate: 15.2 per 100 people
--- 61.9% lower than state average
--- 64.9% lower than national average

#35. Mccook County

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#35. Mccook County

- Opioid dispensing rate: 18.3 per 100 people
--- 54.1% lower than state average
--- 57.7% lower than national average

#34. Lake County

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#34. Lake County

- Opioid dispensing rate: 19.3 per 100 people
--- 51.6% lower than state average
--- 55.4% lower than national average

#33. Brookings County

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#33. Brookings County

- Opioid dispensing rate: 19.8 per 100 people
--- 50.4% lower than state average
--- 54.3% lower than national average

#32. Aurora County

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#32. Aurora County

- Opioid dispensing rate: 21.1 per 100 people
--- 47.1% lower than state average
--- 51.3% lower than national average

#31. Faulk County

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#31. Faulk County

- Opioid dispensing rate: 22.1 per 100 people
--- 44.6% lower than state average
--- 49.0% lower than national average

#30. Charles Mix County

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#30. Charles Mix County

- Opioid dispensing rate: 22.1 per 100 people
--- 44.6% lower than state average
--- 49.0% lower than national average

#29. Douglas County

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#29. Douglas County

- Opioid dispensing rate: 23.1 per 100 people
--- 42.1% lower than state average
--- 46.7% lower than national average

#28. Kingsbury County

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#28. Kingsbury County

- Opioid dispensing rate: 23.9 per 100 people
--- 40.1% lower than state average
--- 44.8% lower than national average

#27. Clay County

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#27. Clay County

- Opioid dispensing rate: 25.6 per 100 people
--- 35.8% lower than state average
--- 40.9% lower than national average

#26. Grant County

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#26. Grant County

- Opioid dispensing rate: 27.8 per 100 people
--- 30.3% lower than state average
--- 35.8% lower than national average

#25. Custer County

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#25. Custer County

- Opioid dispensing rate: 29.9 per 100 people
--- 25.1% lower than state average
--- 30.9% lower than national average

#24. Lincoln County

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#24. Lincoln County

- Opioid dispensing rate: 30.5 per 100 people
--- 23.6% lower than state average
--- 29.6% lower than national average

#23. Jones County

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#23. Jones County

- Opioid dispensing rate: 31.2 per 100 people
--- 21.8% lower than state average
--- 27.9% lower than national average

#22. Roberts County

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#22. Roberts County

- Opioid dispensing rate: 31.7 per 100 people
--- 20.6% lower than state average
--- 26.8% lower than national average

#21. Lawrence County

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#21. Lawrence County

- Opioid dispensing rate: 31.7 per 100 people
--- 20.6% lower than state average
--- 26.8% lower than national average

#20. Walworth County

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#20. Walworth County

- Opioid dispensing rate: 31.8 per 100 people
--- 20.3% lower than state average
--- 26.6% lower than national average

#19. Edmunds County

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#19. Edmunds County

- Opioid dispensing rate: 33.2 per 100 people
--- 16.8% lower than state average
--- 23.3% lower than national average

#18. Beadle County

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#18. Beadle County

- Opioid dispensing rate: 36.7 per 100 people
--- 8.0% lower than state average
--- 15.2% lower than national average

#17. Codington County

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#17. Codington County

- Opioid dispensing rate: 37.2 per 100 people
--- 6.8% lower than state average
--- 14.1% lower than national average

#16. Hyde County

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#16. Hyde County

- Opioid dispensing rate: 38.2 per 100 people
--- 4.3% lower than state average
--- 11.8% lower than national average

#15. Fall River County

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#15. Fall River County

- Opioid dispensing rate: 38.7 per 100 people
--- 3.0% lower than state average
--- 10.6% lower than national average

#14. Hughes County

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#14. Hughes County

- Opioid dispensing rate: 39.6 per 100 people
--- 0.8% lower than state average
--- 8.5% lower than national average

#13. Tripp County

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#13. Tripp County

- Opioid dispensing rate: 42.2 per 100 people
--- 5.8% higher than state average
--- 2.5% lower than national average

#12. Davison County

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#12. Davison County

- Opioid dispensing rate: 45.8 per 100 people
--- 14.8% higher than state average
--- 5.8% higher than national average

#11. Pennington County

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#11. Pennington County

- Opioid dispensing rate: 49.7 per 100 people
--- 24.6% higher than state average
--- 14.8% higher than national average

#10. Yankton County

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#10. Yankton County

- Opioid dispensing rate: 50.0 per 100 people
--- 25.3% higher than state average
--- 15.5% higher than national average

#9. Brule County

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#9. Brule County

- Opioid dispensing rate: 52.1 per 100 people
--- 30.6% higher than state average
--- 20.3% higher than national average

#8. Perkins County

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#8. Perkins County

- Opioid dispensing rate: 53.1 per 100 people
--- 33.1% higher than state average
--- 22.6% higher than national average

#7. Minnehaha County

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#7. Minnehaha County

- Opioid dispensing rate: 53.9 per 100 people
--- 35.1% higher than state average
--- 24.5% higher than national average

#6. Hutchinson County

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#6. Hutchinson County

- Opioid dispensing rate: 54.8 per 100 people
--- 37.3% higher than state average
--- 26.6% higher than national average

#5. Brown County

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#5. Brown County

- Opioid dispensing rate: 55.8 per 100 people
--- 39.8% higher than state average
--- 28.9% higher than national average

#4. Gregory County

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#4. Gregory County

- Opioid dispensing rate: 60.0 per 100 people
--- 50.4% higher than state average
--- 38.6% higher than national average

#3. Jerauld County

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#3. Jerauld County

- Opioid dispensing rate: 108.1 per 100 people
--- 170.9% higher than state average
--- 149.7% higher than national average

#2. Haakon County

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#2. Haakon County

- Opioid dispensing rate: 119.1 per 100 people
--- 198.5% higher than state average
--- 175.1% higher than national average

#1. Union County

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#1. Union County

- Opioid dispensing rate: 233.8 per 100 people
--- 486.0% higher than state average
--- 440.0% higher than national average