Counties with the highest STI rates in Illinois

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March 18, 2024
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Counties with the highest STI rates in Illinois

Sexually transmitted infections are on the rise, putting more people at risk as they spread. Chlamydia rates have nearly doubled since 2000, while the rate of gonorrhea went up by 50% over the same period. The Centers for Disease Control and Prevention reports that syphilis rates are reaching levels last seen in the 1950s.

But some regions of the U.S. are seeing higher rates than others.

Stacker used CDC data to look at which counties reported the highest rate of sexually transmitted infections in Illinois. Counties are ranked by the rate of chlamydia infections, the most prominent STI at the national level, with gonorrhea and then syphilis rates serving as tiebreakers. This story focuses on bacterial infections, which can be cured, rather than viral infections such as HIV and herpes. At the county level, 2021 cases are the most recent available from the CDC, but state and national-level data for 2022 are also included. This story focuses on sexual transmissions and does not include congenital syphilis cases that were inherited from the mother.

Condoms are the most effective way to prevent the spread of STIs for people with multiple sexual partners, but research has found a decreasing rate of condom use among straight, bisexual, and gay male populations.

During the HIV/AIDS epidemic throughout the 1980s and 1990s, public health efforts advocating for condom use helped curb the spread of the virus. Today, however, condoms are no longer the only tool. Pills such as PrEP lower the risk of contracting HIV from sex by as much as 99%.

While more recent data is not available, the latest CDC survey from 2011-2015 showed less than half of unmarried men used condoms during the last time they had sex.

Among high school students having sex, the share using condoms has fallen from 60% in 2011 to 52% in 2021. While one-third of sexually active students used hormonal birth control, only 10% used both condoms and birth control. Methods like the pill and IUDs are effective at preventing pregnancy but do not stop the spread of STIs.

Chlamydia, gonorrhea, and syphilis are technically bacterial infections—meaning they can be cured with antibiotics—but they can still have lasting health impacts, including pelvic inflammatory disease and infertility. These risks are heightened when left untreated, which many STIs are as they don't obviously present themselves.

The CDC recommends annual testing for cisgender women, transgender men, and gender-nonconforming people with cervixes. It also recommends annual testing for males with male sexual partners. People in these groups who frequently have sex with anonymous partners should be tested every three to six months. Anyone with symptoms should always get tested according to the guidelines.

The CDC says there is little evidence that screening among straight men lowers the spread, and the agency's limited budget is put towards programs benefiting the most at-risk groups. However, some public health groups advocate for testing among all people regardless of sex and sexual orientation.

Data from the National Survey of Family Growth shows men on average have more opposite-sex sexual partners than women, and some argue that catching STIs throughout a sexual network rather than just for the most at-risk groups could curb their spread.

Soon, a pill may also help counter the spread of STIs. DoxyPEP can be taken 24 to 72 hours after unprotected sex and stops an STI before it becomes spreadable and symptomatic. The CDC has shared proposed guidelines recommending it for men who have sex with men and transgender women. The drug was originally approved for treating inhalation of anthrax, and doctors can prescribe it for off-label use.

Read on to see how STI infection rates in Illinois compare nationally, and the top counties.

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Emma Rubin // Stacker

State-level statistics

- Chlamydia cases: 568.8 per 100K (#9 nationally, 71,564 cases)
- Gonorrhea cases: 210.2 per 100K (#16 nationally, 26,442 cases)
- Primary and secondary syphilis cases: 11.6 per 100K (#35 nationally, 1,457 cases)
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#50. Union County

- Chlamydia cases: 271.8 per 100K people (46 cases)
- Gonorrhea cases: 35.5 per 100K people (6 cases)
- Syphilis cases (non-congenital): 11.8 per 100K people (2 cases)
--- Primary and secondary syphilis: 5.9 per 100K people (1 case)
--- Nonprimary and nonsecondary early syphilis: 5.9 per 100K people (1 case)
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#49. Montgomery County

- Chlamydia cases: 277.7 per 100K people (78 cases)
- Gonorrhea cases: 138.9 per 100K people (39 cases)
- Syphilis cases (non-congenital): 3.6 per 100K people (1 case)
--- Primary and secondary syphilis: 3.6 per 100K people (1 case)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#48. Whiteside County

- Chlamydia cases: 280.3 per 100K people (155 cases)
- Gonorrhea cases: 77.8 per 100K people (43 cases)
- Syphilis cases (non-congenital): 1.8 per 100K people (1 case)
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 1.8 per 100K people (1 case)
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Leigh Trail // Shutterstock

#47. De Witt County

- Chlamydia cases: 280.3 per 100K people (43 cases)
- Gonorrhea cases: 78.2 per 100K people (12 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#46. Clark County

- Chlamydia cases: 281.0 per 100K people (43 cases)
- Gonorrhea cases: 130.7 per 100K people (20 cases)
- Syphilis cases (non-congenital): 6.5 per 100K people (1 case)
--- Primary and secondary syphilis: 6.5 per 100K people (1 case)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#45. Douglas County

- Chlamydia cases: 283.9 per 100K people (56 cases)
- Gonorrhea cases: 60.8 per 100K people (12 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#44. Hancock County

- Chlamydia cases: 287.4 per 100K people (50 cases)
- Gonorrhea cases: 97.7 per 100K people (17 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#43. Wayne County

- Chlamydia cases: 288.2 per 100K people (46 cases)
- Gonorrhea cases: 181.7 per 100K people (29 cases)
- Syphilis cases (non-congenital): 6.3 per 100K people (1 case)
--- Primary and secondary syphilis: 6.3 per 100K people (1 case)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#42. Greene County

- Chlamydia cases: 295.5 per 100K people (35 cases)
- Gonorrhea cases: 118.2 per 100K people (14 cases)
- Syphilis cases (non-congenital): 16.9 per 100K people (2 cases)
--- Primary and secondary syphilis: 16.9 per 100K people (2 cases)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#41. Cumberland County

- Chlamydia cases: 299.7 per 100K people (31 case)
- Gonorrhea cases: 67.7 per 100K people (7 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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PICTOR PICTURES // Shutterstock

#40. Henderson County

- Chlamydia cases: 301.0 per 100K people (19 cases)
- Gonorrhea cases: 95.1 per 100K people (6 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#39. Stark County

- Chlamydia cases: 302.2 per 100K people (16 cases)
- Gonorrhea cases: 37.8 per 100K people (2 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#38. Kendall County

- Chlamydia cases: 302.5 per 100K people (408 cases)
- Gonorrhea cases: 77.1 per 100K people (104 cases)
- Syphilis cases (non-congenital): 8.2 per 100K people (11 case)
--- Primary and secondary syphilis: 2.2 per 100K people (3 cases)
--- Nonprimary and nonsecondary early syphilis: 5.9 per 100K people (8 cases)
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#37. Henry County

- Chlamydia cases: 312.8 per 100K people (153 cases)
- Gonorrhea cases: 94.1 per 100K people (46 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#36. Richland County

- Chlamydia cases: 322.9 per 100K people (51 case)
- Gonorrhea cases: 196.3 per 100K people (31 case)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#35. Boone County

- Chlamydia cases: 325.4 per 100K people (173 cases)
- Gonorrhea cases: 37.6 per 100K people (20 cases)
- Syphilis cases (non-congenital): 13.2 per 100K people (7 cases)
--- Primary and secondary syphilis: 11.3 per 100K people (6 cases)
--- Nonprimary and nonsecondary early syphilis: 1.9 per 100K people (1 case)
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#34. Edgar County

- Chlamydia cases: 357.1 per 100K people (59 cases)
- Gonorrhea cases: 296.6 per 100K people (49 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#33. Moultrie County

- Chlamydia cases: 358.4 per 100K people (52 cases)
- Gonorrhea cases: 48.2 per 100K people (7 cases)
- Syphilis cases (non-congenital): 6.9 per 100K people (1 case)
--- Primary and secondary syphilis: 6.9 per 100K people (1 case)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#32. Jefferson County

- Chlamydia cases: 379.6 per 100K people (140 cases)
- Gonorrhea cases: 162.7 per 100K people (60 cases)
- Syphilis cases (non-congenital): 5.4 per 100K people (2 cases)
--- Primary and secondary syphilis: 2.7 per 100K people (1 case)
--- Nonprimary and nonsecondary early syphilis: 2.7 per 100K people (1 case)
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#31. Will County

- Chlamydia cases: 381.9 per 100K people (2,663 cases)
- Gonorrhea cases: 108.9 per 100K people (759 cases)
- Syphilis cases (non-congenital): 9.5 per 100K people (66 cases)
--- Primary and secondary syphilis: 5.7 per 100K people (40 cases)
--- Nonprimary and nonsecondary early syphilis: 3.7 per 100K people (26 cases)
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#30. Franklin County

- Chlamydia cases: 384.6 per 100K people (144 cases)
- Gonorrhea cases: 213.7 per 100K people (80 cases)
- Syphilis cases (non-congenital): 8.0 per 100K people (3 cases)
--- Primary and secondary syphilis: 5.3 per 100K people (2 cases)
--- Nonprimary and nonsecondary early syphilis: 2.7 per 100K people (1 case)
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#29. Kane County

- Chlamydia cases: 387.9 per 100K people (2,000 cases)
- Gonorrhea cases: 89.2 per 100K people (460 cases)
- Syphilis cases (non-congenital): 10.5 per 100K people (54 cases)
--- Primary and secondary syphilis: 6.4 per 100K people (33 cases)
--- Nonprimary and nonsecondary early syphilis: 4.1 per 100K people (21 case)
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#28. Marion County

- Chlamydia cases: 398.5 per 100K people (149 cases)
- Gonorrhea cases: 224.7 per 100K people (84 cases)
- Syphilis cases (non-congenital): 8.0 per 100K people (3 cases)
--- Primary and secondary syphilis: 5.3 per 100K people (2 cases)
--- Nonprimary and nonsecondary early syphilis: 2.7 per 100K people (1 case)
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#27. Williamson County

- Chlamydia cases: 414.2 per 100K people (277 cases)
- Gonorrhea cases: 276.6 per 100K people (185 cases)
- Syphilis cases (non-congenital): 13.5 per 100K people (9 cases)
--- Primary and secondary syphilis: 6.0 per 100K people (4 cases)
--- Nonprimary and nonsecondary early syphilis: 7.5 per 100K people (5 cases)
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#26. Adams County

- Chlamydia cases: 448.0 per 100K people (291 case)
- Gonorrhea cases: 167.8 per 100K people (109 cases)
- Syphilis cases (non-congenital): 4.6 per 100K people (3 cases)
--- Primary and secondary syphilis: 4.6 per 100K people (3 cases)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#25. Lake County

- Chlamydia cases: 448.8 per 100K people (3,192 cases)
- Gonorrhea cases: 92.4 per 100K people (657 cases)
- Syphilis cases (non-congenital): 2.4 per 100K people (17 cases)
--- Primary and secondary syphilis: .7 per 100K people (5 cases)
--- Nonprimary and nonsecondary early syphilis: 1.7 per 100K people (12 cases)
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#24. Madison County

- Chlamydia cases: 449.2 per 100K people (1,188 cases)
- Gonorrhea cases: 217.8 per 100K people (576 cases)
- Syphilis cases (non-congenital): 7.9 per 100K people (21 case)
--- Primary and secondary syphilis: 6.4 per 100K people (17 cases)
--- Nonprimary and nonsecondary early syphilis: 1.5 per 100K people (4 cases)
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#23. Saline County

- Chlamydia cases: 450.3 per 100K people (105 cases)
- Gonorrhea cases: 244.4 per 100K people (57 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#22. Knox County

- Chlamydia cases: 468.9 per 100K people (231 case)
- Gonorrhea cases: 188.8 per 100K people (93 cases)
- Syphilis cases (non-congenital): 12.2 per 100K people (6 cases)
--- Primary and secondary syphilis: 10.1 per 100K people (5 cases)
--- Nonprimary and nonsecondary early syphilis: 2.0 per 100K people (1 case)
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#21. Logan County

- Chlamydia cases: 503.7 per 100K people (141 case)
- Gonorrhea cases: 300.1 per 100K people (84 cases)
- Syphilis cases (non-congenital): 7.1 per 100K people (2 cases)
--- Primary and secondary syphilis: 7.1 per 100K people (2 cases)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#20. Stephenson County

- Chlamydia cases: 529.3 per 100K people (233 cases)
- Gonorrhea cases: 168.1 per 100K people (74 cases)
- Syphilis cases (non-congenital): 6.8 per 100K people (3 cases)
--- Primary and secondary syphilis: 4.5 per 100K people (2 cases)
--- Nonprimary and nonsecondary early syphilis: 2.3 per 100K people (1 case)
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#19. Dekalb County

- Chlamydia cases: 535.8 per 100K people (538 cases)
- Gonorrhea cases: 167.3 per 100K people (168 cases)
- Syphilis cases (non-congenital): 8.0 per 100K people (8 cases)
--- Primary and secondary syphilis: 5.0 per 100K people (5 cases)
--- Nonprimary and nonsecondary early syphilis: 3.0 per 100K people (3 cases)
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#18. Rock Island County

- Chlamydia cases: 545.8 per 100K people (780 cases)
- Gonorrhea cases: 263.1 per 100K people (376 cases)
- Syphilis cases (non-congenital): 11.9 per 100K people (17 cases)
--- Primary and secondary syphilis: 7.7 per 100K people (11 case)
--- Nonprimary and nonsecondary early syphilis: 4.2 per 100K people (6 cases)
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#17. Morgan County

- Chlamydia cases: 561.2 per 100K people (183 cases)
- Gonorrhea cases: 282.2 per 100K people (92 cases)
- Syphilis cases (non-congenital): 6.1 per 100K people (2 cases)
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 6.1 per 100K people (2 cases)
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#16. Cass County

- Chlamydia cases: 563.7 per 100K people (72 cases)
- Gonorrhea cases: 195.7 per 100K people (25 cases)
- Syphilis cases (non-congenital): 15.7 per 100K people (2 cases)
--- Primary and secondary syphilis: 7.8 per 100K people (1 case)
--- Nonprimary and nonsecondary early syphilis: 7.8 per 100K people (1 case)
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#15. Mclean County

- Chlamydia cases: 572.3 per 100K people (978 cases)
- Gonorrhea cases: 192.5 per 100K people (329 cases)
- Syphilis cases (non-congenital): 7.6 per 100K people (13 cases)
--- Primary and secondary syphilis: 4.1 per 100K people (7 cases)
--- Nonprimary and nonsecondary early syphilis: 3.5 per 100K people (6 cases)
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#14. Kankakee County

- Chlamydia cases: 595.7 per 100K people (635 cases)
- Gonorrhea cases: 307.7 per 100K people (328 cases)
- Syphilis cases (non-congenital): 2.8 per 100K people (3 cases)
--- Primary and secondary syphilis: 1.9 per 100K people (2 cases)
--- Nonprimary and nonsecondary early syphilis: .9 per 100K people (1 case)
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#13. Pulaski County

- Chlamydia cases: 612.0 per 100K people (31 case)
- Gonorrhea cases: 355.4 per 100K people (18 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#12. Sangamon County

- Chlamydia cases: 675.3 per 100K people (1,315 cases)
- Gonorrhea cases: 422.6 per 100K people (823 cases)
- Syphilis cases (non-congenital): 22.1 per 100K people (43 cases)
--- Primary and secondary syphilis: 16.4 per 100K people (32 cases)
--- Nonprimary and nonsecondary early syphilis: 5.6 per 100K people (11 case)
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#11. Winnebago County

- Chlamydia cases: 716.7 per 100K people (2,029 cases)
- Gonorrhea cases: 325.7 per 100K people (922 cases)
- Syphilis cases (non-congenital): 29.3 per 100K people (83 cases)
--- Primary and secondary syphilis: 15.2 per 100K people (43 cases)
--- Nonprimary and nonsecondary early syphilis: 14.1 per 100K people (40 cases)
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Roberto Galan // Shutterstock

#10. Coles County

- Chlamydia cases: 729.2 per 100K people (341 case)
- Gonorrhea cases: 256.6 per 100K people (120 cases)
- Syphilis cases (non-congenital): 2.1 per 100K people (1 case)
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 2.1 per 100K people (1 case)
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#9. Mcdonough County

- Chlamydia cases: 764.1 per 100K people (205 cases)
- Gonorrhea cases: 234.8 per 100K people (63 cases)
- Syphilis cases (non-congenital): 7.5 per 100K people (2 cases)
--- Primary and secondary syphilis: 7.5 per 100K people (2 cases)
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#8. Cook County

- Chlamydia cases: 764.3 per 100K people (39,536 cases)
- Gonorrhea cases: 343.0 per 100K people (17,744 cases)
- Syphilis cases (non-congenital): 37.2 per 100K people (1,922 cases)
--- Primary and secondary syphilis: 19.8 per 100K people (1,024 cases)
--- Nonprimary and nonsecondary early syphilis: 17.4 per 100K people (898 cases)
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#7. St. Clair County

- Chlamydia cases: 774.7 per 100K people (1,974 cases)
- Gonorrhea cases: 402.7 per 100K people (1,026 cases)
- Syphilis cases (non-congenital): 33.4 per 100K people (85 cases)
--- Primary and secondary syphilis: 22.8 per 100K people (58 cases)
--- Nonprimary and nonsecondary early syphilis: 10.6 per 100K people (27 cases)
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Roberto Galan // Shutterstock

#6. Alexander County

- Chlamydia cases: 775.3 per 100K people (39 cases)
- Gonorrhea cases: 457.3 per 100K people (23 cases)
- Syphilis cases (non-congenital): 0 cases
--- Primary and secondary syphilis: 0 cases
--- Nonprimary and nonsecondary early syphilis: 0 cases
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#5. Champaign County

- Chlamydia cases: 784.7 per 100K people (1,616 cases)
- Gonorrhea cases: 350.1 per 100K people (721 case)
- Syphilis cases (non-congenital): 14.6 per 100K people (30 cases)
--- Primary and secondary syphilis: 7.3 per 100K people (15 cases)
--- Nonprimary and nonsecondary early syphilis: 7.3 per 100K people (15 cases)
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Roberto Galan // Shutterstock

#4. Vermilion County

- Chlamydia cases: 786.6 per 100K people (575 cases)
- Gonorrhea cases: 469.3 per 100K people (343 cases)
- Syphilis cases (non-congenital): 20.5 per 100K people (15 cases)
--- Primary and secondary syphilis: 16.4 per 100K people (12 cases)
--- Nonprimary and nonsecondary early syphilis: 4.1 per 100K people (3 cases)
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#3. Peoria County

- Chlamydia cases: 849.3 per 100K people (1,524 cases)
- Gonorrhea cases: 585.7 per 100K people (1,051 case)
- Syphilis cases (non-congenital): 21.7 per 100K people (39 cases)
--- Primary and secondary syphilis: 16.7 per 100K people (30 cases)
--- Nonprimary and nonsecondary early syphilis: 5.0 per 100K people (9 cases)
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#2. Macon County

- Chlamydia cases: 857.2 per 100K people (878 cases)
- Gonorrhea cases: 577.0 per 100K people (591 case)
- Syphilis cases (non-congenital): 10.7 per 100K people (11 case)
--- Primary and secondary syphilis: 9.8 per 100K people (10 cases)
--- Nonprimary and nonsecondary early syphilis: 1.0 per 100K people (1 case)
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#1. Jackson County

- Chlamydia cases: 981.6 per 100K people (516 cases)
- Gonorrhea cases: 635.4 per 100K people (334 cases)
- Syphilis cases (non-congenital): 45.7 per 100K people (24 cases)
--- Primary and secondary syphilis: 28.5 per 100K people (15 cases)
--- Nonprimary and nonsecondary early syphilis: 17.1 per 100K people (9 cases)

This story features data reporting and writing by Emma Rubin and is part of a series utilizing data automation across 49 states.

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