Counties with highest COVID-19 infection rates in North Carolina

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May 21, 2022
Bz3rk // Wikimedia Commons

Counties with highest COVID-19 infection rates in North Carolina

The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.

Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely.

The United States as of May 25 reached over 1 million COVID-19-related deaths and 83.6 million COVID-19 cases, according to Johns Hopkins University. Currently, 66.6% of the population is fully vaccinated, and 46.6% of vaccinated people have received booster doses.

Stacker compiled a list of the counties with highest COVID-19 infection rates in North Carolina using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to May 24, 2022. Cumulative cases per 100,000 served as a tiebreaker.

Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.

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Upstateherd // Wikimedia Commons

#50. Wilkes County, NC

- New cases per 100k in the past week: 88 (60 new cases, -22% change from previous week)
- Cumulative cases per 100k: 25,890 (17,712 total cases)
--- 0.1% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 389 (266 total deaths)
--- 65.5% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 46.8% (32,004 fully vaccinated)
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Indy beetle // Wikimedia Commons

#49. Pender County, NC

- New cases per 100k in the past week: 89 (56 new cases, -14% change from previous week)
- Cumulative cases per 100k: 24,569 (15,493 total cases)
--- 5.2% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 203 (128 total deaths)
--- 13.6% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 51.5% (32,486 fully vaccinated)
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Wasrts // Wikimedia Commons

#48. Yadkin County, NC

- New cases per 100k in the past week: 90 (34 new cases, -37% change from previous week)
- Cumulative cases per 100k: 29,509 (11,115 total cases)
--- 13.9% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 321 (121 total deaths)
--- 36.6% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 49.5% (18,640 fully vaccinated)
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Travis K. Witt // Wikimedia Commons

#47. Iredell County, NC

- New cases per 100k in the past week: 91 (165 new cases, -38% change from previous week)
- Cumulative cases per 100k: 27,105 (49,279 total cases)
--- 4.6% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 256 (466 total deaths)
--- 8.9% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 53.2% (96,771 fully vaccinated)
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CZmarlin — Christopher Ziemnowicz // Wikimedia Commons

#46. Hoke County, NC

- New cases per 100k in the past week: 91 (50 new cases, -49% change from previous week)
- Cumulative cases per 100k: 27,479 (15,178 total cases)
--- 6.0% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 210 (116 total deaths)
--- 10.6% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 41.9% (23,145 fully vaccinated)
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BrendaByrneGreene // Wikimedia Commons

#45. Nash County, NC

- New cases per 100k in the past week: 91 (86 new cases, +15% change from previous week)
- Cumulative cases per 100k: 28,238 (26,628 total cases)
--- 9.0% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 328 (309 total deaths)
--- 39.6% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 57.6% (54,354 fully vaccinated)
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Indy beetle // Wikimedia Commons

#44. Harnett County, NC

- New cases per 100k in the past week: 92 (125 new cases, -27% change from previous week)
- Cumulative cases per 100k: 24,999 (33,992 total cases)
--- 3.5% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 249 (339 total deaths)
--- 6.0% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 43.1% (58,623 fully vaccinated)
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Nikola Spasic Photography // Shutterstock

#43. Pitt County, NC

- New cases per 100k in the past week: 92 (167 new cases, -37% change from previous week)
- Cumulative cases per 100k: 29,393 (53,125 total cases)
--- 13.4% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 123 (223 total deaths)
--- 47.7% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 53.7% (97,035 fully vaccinated)
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Upstateherd // Wikimedia Commons

#42. Mitchell County, NC

- New cases per 100k in the past week: 94 (14 new cases, +180% change from previous week)
- Cumulative cases per 100k: 23,323 (3,490 total cases)
--- 10.0% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 247 (37 total deaths)
--- 5.1% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 48.4% (7,247 fully vaccinated)
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Upstateherd // Wikimedia Commons

#41. Anson County, NC

- New cases per 100k in the past week: 94 (23 new cases, +5% change from previous week)
- Cumulative cases per 100k: 26,998 (6,600 total cases)
--- 4.2% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 413 (101 total deaths)
--- 75.7% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 47.1% (11,510 fully vaccinated)
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Jerrye & Roy Klotz, MD // Wikimedia Commons

#40. Richmond County, NC

- New cases per 100k in the past week: 94 (42 new cases, -19% change from previous week)
- Cumulative cases per 100k: 28,954 (12,980 total cases)
--- 11.7% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 428 (192 total deaths)
--- 82.1% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 48.3% (21,632 fully vaccinated)
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Ymblanter // Wikimedia Commons

#39. Washington County, NC

- New cases per 100k in the past week: 95 (11 new cases, +120% change from previous week)
- Cumulative cases per 100k: 26,520 (3,071 total cases)
--- 2.3% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 432 (50 total deaths)
--- 83.8% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 51.1% (5,917 fully vaccinated)
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#38. Onslow County, NC

- New cases per 100k in the past week: 98 (193 new cases, -23% change from previous week)
- Cumulative cases per 100k: 26,584 (52,620 total cases)
--- 2.6% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 191 (378 total deaths)
--- 18.7% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 61.2% (121,202 fully vaccinated)
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KAD Photo // Shutterstock

#37. Moore County, NC

- New cases per 100k in the past week: 100 (101 new cases, -33% change from previous week)
- Cumulative cases per 100k: 24,553 (24,769 total cases)
--- 5.2% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 322 (325 total deaths)
--- 37.0% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 57.9% (58,419 fully vaccinated)
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Washuotaku // Wikimedia Commons

#36. Lincoln County, NC

- New cases per 100k in the past week: 100 (86 new cases, -15% change from previous week)
- Cumulative cases per 100k: 28,655 (24,675 total cases)
--- 10.6% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 202 (174 total deaths)
--- 14.0% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 49.9% (42,970 fully vaccinated)
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Jacalyn Engler // Wikimedia Commons

#35. Stokes County, NC

- New cases per 100k in the past week: 101 (46 new cases, -43% change from previous week)
- Cumulative cases per 100k: 25,016 (11,405 total cases)
--- 3.5% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 397 (181 total deaths)
--- 68.9% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 47.4% (21,603 fully vaccinated)
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KimWrenn // Wikimedia Commons

#34. Vance County, NC

- New cases per 100k in the past week: 101 (45 new cases, -35% change from previous week)
- Cumulative cases per 100k: 26,990 (12,020 total cases)
--- 4.2% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 274 (122 total deaths)
--- 16.6% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 57.9% (25,779 fully vaccinated)
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#33. Haywood County, NC

- New cases per 100k in the past week: 108 (67 new cases, -27% change from previous week)
- Cumulative cases per 100k: 21,290 (13,267 total cases)
--- 17.8% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 355 (221 total deaths)
--- 51.1% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 57.4% (35,761 fully vaccinated)
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#32. Cumberland County, NC

- New cases per 100k in the past week: 108 (364 new cases, -33% change from previous week)
- Cumulative cases per 100k: 26,408 (88,602 total cases)
--- 1.9% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 188 (631 total deaths)
--- 20.0% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 60.7% (203,524 fully vaccinated)
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Upstateherd // Wikimedia Commons

#31. Gaston County, NC

- New cases per 100k in the past week: 108 (242 new cases, -13% change from previous week)
- Cumulative cases per 100k: 29,489 (66,212 total cases)
--- 13.8% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 379 (851 total deaths)
--- 61.3% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 50.2% (112,665 fully vaccinated)
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NatalieMaynor from Jackson, Mississippi, USA // Wikimedia Commons

#30. Caswell County, NC

- New cases per 100k in the past week: 111 (25 new cases, -47% change from previous week)
- Cumulative cases per 100k: 23,943 (5,412 total cases)
--- 7.6% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 212 (48 total deaths)
--- 9.8% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 47.4% (10,715 fully vaccinated)
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Ammodramus // Wikimedia Commons

#29. Johnston County, NC

- New cases per 100k in the past week: 111 (232 new cases, -38% change from previous week)
- Cumulative cases per 100k: 29,018 (60,745 total cases)
--- 12.0% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 216 (452 total deaths)
--- 8.1% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 54.2% (113,498 fully vaccinated)
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Cecouchman // Wikimedia Commons

#28. Halifax County, NC

- New cases per 100k in the past week: 112 (56 new cases, -5% change from previous week)
- Cumulative cases per 100k: 28,236 (14,121 total cases)
--- 9.0% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 374 (187 total deaths)
--- 59.1% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 53.8% (26,898 fully vaccinated)
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Nyttend // Wikimedia Commons

#27. Scotland County, NC

- New cases per 100k in the past week: 112 (39 new cases, -17% change from previous week)
- Cumulative cases per 100k: 29,236 (10,181 total cases)
--- 12.8% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 379 (132 total deaths)
--- 61.3% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 49.5% (17,238 fully vaccinated)
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MarkVanDykePhotography // Shutterstock

#26. Dare County, NC

- New cases per 100k in the past week: 116 (43 new cases, -48% change from previous week)
- Cumulative cases per 100k: 20,711 (7,665 total cases)
--- 20.1% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 73 (27 total deaths)
--- 68.9% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 73.0% (27,024 fully vaccinated)
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ncwetlands.org// Wikimedia Commons

#25. Bladen County, NC

- New cases per 100k in the past week: 116 (38 new cases, +19% change from previous week)
- Cumulative cases per 100k: 28,776 (9,416 total cases)
--- 11.0% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 388 (127 total deaths)
--- 65.1% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 64.4% (21,083 fully vaccinated)
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Ceh2624 // Wikimedia Commons

#24. Davie County, NC

- New cases per 100k in the past week: 117 (50 new cases, -43% change from previous week)
- Cumulative cases per 100k: 26,635 (11,412 total cases)
--- 2.8% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 243 (104 total deaths)
--- 3.4% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 57.5% (24,637 fully vaccinated)
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#23. Craven County, NC

- New cases per 100k in the past week: 118 (121 new cases, -48% change from previous week)
- Cumulative cases per 100k: 24,449 (24,972 total cases)
--- 5.6% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 203 (207 total deaths)
--- 13.6% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 62.8% (64,125 fully vaccinated)
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Katangais // Wikimedia Commons

#22. Robeson County, NC

- New cases per 100k in the past week: 118 (154 new cases, -16% change from previous week)
- Cumulative cases per 100k: 31,326 (40,920 total cases)
--- 20.9% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 412 (538 total deaths)
--- 75.3% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 42.7% (55,797 fully vaccinated)
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Beckycafferylepage // Wikimedia Commons

#21. Union County, NC

- New cases per 100k in the past week: 122 (293 new cases, -33% change from previous week)
- Cumulative cases per 100k: 26,348 (63,199 total cases)
--- 1.7% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 204 (490 total deaths)
--- 13.2% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 55.5% (133,065 fully vaccinated)
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Toribio93 // Shutterstock

#20. Madison County, NC

- New cases per 100k in the past week: 124 (27 new cases, -16% change from previous week)
- Cumulative cases per 100k: 24,050 (5,232 total cases)
--- 7.2% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 372 (81 total deaths)
--- 58.3% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 56.5% (12,302 fully vaccinated)
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Doug Kerr from Albany, NY, United States // Wikimedia Commons

#19. Warren County, NC

- New cases per 100k in the past week: 127 (25 new cases, -22% change from previous week)
- Cumulative cases per 100k: 22,371 (4,414 total cases)
--- 13.7% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 233 (46 total deaths)
--- 0.9% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 55.2% (10,892 fully vaccinated)
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Sean Pavone // Shutterstock

#18. Forsyth County, NC

- New cases per 100k in the past week: 136 (521 new cases, -34% change from previous week)
- Cumulative cases per 100k: 24,907 (95,219 total cases)
--- 3.9% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 215 (823 total deaths)
--- 8.5% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 62.2% (237,696 fully vaccinated)
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PHHI // Wikimedia Commons

#17. Cabarrus County, NC

- New cases per 100k in the past week: 136 (295 new cases, -22% change from previous week)
- Cumulative cases per 100k: 26,371 (57,081 total cases)
--- 1.8% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 228 (494 total deaths)
--- 3.0% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 55.9% (121,019 fully vaccinated)
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Warren LeMay // Wikimedia Commons

#16. Alamance County, NC

- New cases per 100k in the past week: 137 (233 new cases, -43% change from previous week)
- Cumulative cases per 100k: 28,414 (48,164 total cases)
--- 9.7% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 288 (488 total deaths)
--- 22.6% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 59.6% (100,961 fully vaccinated)
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Bud Davis, U.S. Army Corps of Engineers // Wikimedia Commons

#15. Pamlico County, NC

- New cases per 100k in the past week: 141 (18 new cases, +80% change from previous week)
- Cumulative cases per 100k: 20,847 (2,653 total cases)
--- 19.6% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 220 (28 total deaths)
--- 6.4% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 55.7% (7,084 fully vaccinated)
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EbonyEaton // Wikimedia Commons

#14. Granville County, NC

- New cases per 100k in the past week: 142 (86 new cases, -8% change from previous week)
- Cumulative cases per 100k: 24,274 (14,672 total cases)
--- 6.3% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 190 (115 total deaths)
--- 19.1% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 62.5% (37,800 fully vaccinated)
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#13. Guilford County, NC

- New cases per 100k in the past week: 146 (785 new cases, -33% change from previous week)
- Cumulative cases per 100k: 22,880 (122,907 total cases)
--- 11.7% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 225 (1,210 total deaths)
--- 4.3% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 61.6% (330,805 fully vaccinated)
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KAD Photo // Shutterstock

#12. Chatham County, NC

- New cases per 100k in the past week: 150 (112 new cases, -39% change from previous week)
- Cumulative cases per 100k: 18,085 (13,468 total cases)
--- 30.2% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 153 (114 total deaths)
--- 34.9% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 58.8% (43,792 fully vaccinated)
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iofoto // Shutterstock

#11. Brunswick County, NC

- New cases per 100k in the past week: 150 (214 new cases, -29% change from previous week)
- Cumulative cases per 100k: 21,632 (30,895 total cases)
--- 16.5% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 232 (332 total deaths)
--- 1.3% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 63.0% (89,928 fully vaccinated)
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digidreamgrafix // Shutterstock

#10. Mecklenburg County, NC

- New cases per 100k in the past week: 154 (1,710 new cases, -33% change from previous week)
- Cumulative cases per 100k: 25,923 (287,837 total cases)
--- 0.0% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 146 (1,623 total deaths)
--- 37.9% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 63.7% (707,281 fully vaccinated)
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Nagel Photography // Shutterstock

#9. Buncombe County, NC

- New cases per 100k in the past week: 158 (412 new cases, -35% change from previous week)
- Cumulative cases per 100k: 21,007 (54,868 total cases)
--- 18.9% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 224 (584 total deaths)
--- 4.7% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 66.0% (172,486 fully vaccinated)
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Bethbrownebooks // Wikimedia Commons

#8. Chowan County, NC

- New cases per 100k in the past week: 158 (22 new cases, +5% change from previous week)
- Cumulative cases per 100k: 30,080 (4,194 total cases)
--- 16.1% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 437 (61 total deaths)
--- 86.0% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 56.5% (7,882 fully vaccinated)
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Nyttend // Wikimedia Commons

#7. Person County, NC

- New cases per 100k in the past week: 165 (65 new cases, +16% change from previous week)
- Cumulative cases per 100k: 24,155 (9,539 total cases)
--- 6.8% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 276 (109 total deaths)
--- 17.4% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 56.7% (22,399 fully vaccinated)
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HarmonyReignPope // Wikimedia Commons

#6. Tyrrell County, NC

- New cases per 100k in the past week: 174 (7 new cases, +133% change from previous week)
- Cumulative cases per 100k: 24,701 (992 total cases)
--- 4.7% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 199 (8 total deaths)
--- 15.3% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 49.3% (1,978 fully vaccinated)
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Bryan Pollard // Shutterstock

#5. Orange County, NC

- New cases per 100k in the past week: 195 (290 new cases, -39% change from previous week)
- Cumulative cases per 100k: 19,359 (28,744 total cases)
--- 25.3% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 90 (134 total deaths)
--- 61.7% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 76.6% (113,735 fully vaccinated)
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Jerrye & Roy Klotz, MD // Wikimedia Commons

#4. Franklin County, NC

- New cases per 100k in the past week: 208 (145 new cases, -13% change from previous week)
- Cumulative cases per 100k: 30,083 (20,963 total cases)
--- 16.1% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 113 (79 total deaths)
--- 51.9% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 54.1% (37,715 fully vaccinated)
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Sean Pavone // Shutterstock

#3. Durham County, NC

- New cases per 100k in the past week: 218 (700 new cases, -38% change from previous week)
- Cumulative cases per 100k: 23,708 (76,218 total cases)
--- 8.5% less cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 105 (338 total deaths)
--- 55.3% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 71.2% (228,972 fully vaccinated)
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#2. Hyde County, NC

- New cases per 100k in the past week: 284 (14 new cases, -7% change from previous week)
- Cumulative cases per 100k: 27,486 (1,357 total cases)
--- 6.1% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 263 (13 total deaths)
--- 11.9% more deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 67.5% (3,331 fully vaccinated)
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Bz3rk // Wikimedia Commons

#1. Wake County, NC

- New cases per 100k in the past week: 294 (3,265 new cases, -25% change from previous week)
- Cumulative cases per 100k: 27,507 (305,812 total cases)
--- 6.2% more cases per 100k residents than North Carolina
- Cumulative deaths per 100k: 101 (1,121 total deaths)
--- 57.0% less deaths per 100k residents than North Carolina
- Population that is fully vaccinated: 73.6% (818,411 fully vaccinated)

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