Counties with the highest COVID-19 vaccination rate in South Carolina

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October 17, 2022
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Counties with the highest COVID-19 vaccination rate in South Carolina

The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.

The United States as of Oct. 28 reached over 1 million COVID-19-related deaths and 97.4 million COVID-19 cases, according to Johns Hopkins University. Currently, 68.4% of the population is fully vaccinated, and 7.3% of people have received the most recent bivalent booster dose.

Stacker compiled a list of the counties with highest COVID-19 vaccination rates in South Carolina using data from the U.S. Department of Health & Human Services and Covid Act Now. Counties are ranked by the highest vaccination rate as of Oct. 27, 2022. Due to inconsistencies in reporting, some counties do not have vaccination data available. Case count data based on Oct. 13 numbers reported by the Department of Health and Human Services. Keep reading to see whether your county ranks among the highest COVID-19 vaccination rates in your state.

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Bill Fitzpatrick // Wikimedia Commons

#46. Saluda County

- Population that is fully vaccinated: 31.2% (6,395 fully vaccinated)
--- 59.5% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 401 (82 total deaths)
--- 11.1% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 21,379 (4,377 total cases)
--- 36.1% less cases per 100k residents than South Carolina
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Morder // Wikimedia Commons

#45. Cherokee County

- Population that is fully vaccinated: 35.2% (20,191 fully vaccinated)
--- 54.3% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 571 (327 total deaths)
--- 58.2% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 30,072 (17,231 total cases)
--- 10.1% less cases per 100k residents than South Carolina
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Upstateherd // Wikimedia Commons

#44. Chesterfield County

- Population that is fully vaccinated: 38.4% (17,525 fully vaccinated)
--- 50.2% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 445 (203 total deaths)
--- 23.3% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 30,618 (13,977 total cases)
--- 8.4% less cases per 100k residents than South Carolina
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Bill Fitzpatrick // Wikimedia Commons

#43. Jasper County

- Population that is fully vaccinated: 39.5% (11,875 fully vaccinated)
--- 48.8% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 316 (95 total deaths)
--- 12.5% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 22,695 (6,825 total cases)
--- 32.1% less cases per 100k residents than South Carolina
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Bill Fitzpatrick // Wikimedia Commons

#42. Laurens County

- Population that is fully vaccinated: 39.7% (26,766 fully vaccinated)
--- 48.5% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 453 (306 total deaths)
--- 25.5% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 31,999 (21,597 total cases)
--- 4.3% less cases per 100k residents than South Carolina
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Brian Scott // Wikimedia Commons

#41. Abbeville County

- Population that is fully vaccinated: 41.5% (10,171 fully vaccinated)
--- 46.2% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 289 (71 total deaths)
--- 19.9% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 29,718 (7,289 total cases)
--- 11.1% less cases per 100k residents than South Carolina
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Upstateherd // Wikimedia Commons

#40. Anderson County

- Population that is fully vaccinated: 41.6% (84,169 fully vaccinated)
--- 46.0% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 517 (1,048 total deaths)
--- 43.2% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 32,508 (65,847 total cases)
--- 2.8% less cases per 100k residents than South Carolina
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Bill Fitzpatrick // Wikimedia Commons

#39. Calhoun County

- Population that is fully vaccinated: 42.5% (6,192 fully vaccinated)
--- 44.9% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 419 (61 total deaths)
--- 16.1% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 23,088 (3,360 total cases)
--- 31.0% less cases per 100k residents than South Carolina
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#38. Union County

- Population that is fully vaccinated: 43.0% (11,750 fully vaccinated)
--- 44.2% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 567 (155 total deaths)
--- 57.1% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 33,047 (9,027 total cases)
--- 1.2% less cases per 100k residents than South Carolina
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#37. Spartanburg County

- Population that is fully vaccinated: 45.0% (144,058 fully vaccinated)
--- 41.6% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 496 (1,585 total deaths)
--- 37.4% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 34,229 (109,458 total cases)
--- 2.4% more cases per 100k residents than South Carolina
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Calvin Beale // Wikimedia Commons

#36. Marlboro County

- Population that is fully vaccinated: 46.1% (12,039 fully vaccinated)
--- 40.2% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 421 (110 total deaths)
--- 16.6% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 35,673 (9,317 total cases)
--- 6.7% more cases per 100k residents than South Carolina
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Bill Fitzpatrick // Wikimedia Commons

#35. Dillon County

- Population that is fully vaccinated: 46.2% (14,077 fully vaccinated)
--- 40.1% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 489 (149 total deaths)
--- 35.5% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 36,008 (10,975 total cases)
--- 7.7% more cases per 100k residents than South Carolina
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Brian Stansberry // Wikimedia Commons

#34. Oconee County

- Population that is fully vaccinated: 46.3% (36,805 fully vaccinated)
--- 39.9% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 453 (360 total deaths)
--- 25.5% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 34,741 (27,635 total cases)
--- 3.9% more cases per 100k residents than South Carolina
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#33. Chester County

- Population that is fully vaccinated: 47.5% (15,307 fully vaccinated)
--- 38.4% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 487 (157 total deaths)
--- 34.9% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 36,428 (11,746 total cases)
--- 8.9% more cases per 100k residents than South Carolina
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KudzuVine // Wikimedia Commons

#32. Pickens County

- Population that is fully vaccinated: 47.8% (60,696 fully vaccinated)
--- 38.0% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 515 (654 total deaths)
--- 42.7% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 40,624 (51,545 total cases)
--- 21.5% more cases per 100k residents than South Carolina
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Festiva76 // Wikimedia Commons

#31. Aiken County

- Population that is fully vaccinated: 48.0% (82,102 fully vaccinated)
--- 37.7% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 261 (446 total deaths)
--- 27.7% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 28,476 (48,658 total cases)
--- 14.8% less cases per 100k residents than South Carolina
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Bill Fitzpatrick // Wikimedia Commons

#30. Greenwood County

- Population that is fully vaccinated: 49.2% (34,824 fully vaccinated)
--- 36.2% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 452 (320 total deaths)
--- 25.2% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 35,790 (25,343 total cases)
--- 7.0% more cases per 100k residents than South Carolina
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Calatayudboy // Wikimedia Commons

#29. Lancaster County

- Population that is fully vaccinated: 49.2% (48,226 fully vaccinated)
--- 36.2% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 297 (291 total deaths)
--- 17.7% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 30,051 (29,454 total cases)
--- 10.1% less cases per 100k residents than South Carolina
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Ammodramus // Wikimedia Commons

#28. Lee County

- Population that is fully vaccinated: 49.4% (8,319 fully vaccinated)
--- 35.9% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 582 (98 total deaths)
--- 61.2% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 28,476 (4,792 total cases)
--- 14.8% less cases per 100k residents than South Carolina
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ProfReader // Wikimedia Commons

#27. Marion County

- Population that is fully vaccinated: 50.1% (15,358 fully vaccinated)
--- 35.0% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 548 (168 total deaths)
--- 51.8% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 32,759 (10,043 total cases)
--- 2.0% less cases per 100k residents than South Carolina
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Upstateherd // Wikimedia Commons

#26. Colleton County

- Population that is fully vaccinated: 50.1% (18,866 fully vaccinated)
--- 35.0% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 592 (223 total deaths)
--- 64.0% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 28,213 (10,630 total cases)
--- 15.6% less cases per 100k residents than South Carolina
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Jud McCranie // Wikimedia Commons

#25. Darlington County

- Population that is fully vaccinated: 50.2% (33,426 fully vaccinated)
--- 34.9% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 495 (330 total deaths)
--- 37.1% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 31,874 (21,234 total cases)
--- 4.7% less cases per 100k residents than South Carolina
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Upstateherd // Wikimedia Commons

#24. Clarendon County

- Population that is fully vaccinated: 50.5% (17,033 fully vaccinated)
--- 34.5% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 486 (164 total deaths)
--- 34.6% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 30,390 (10,255 total cases)
--- 9.1% less cases per 100k residents than South Carolina
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Connor401 // Wikimedia Commons

#23. York County

- Population that is fully vaccinated: 52.2% (146,569 fully vaccinated)
--- 32.3% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 250 (702 total deaths)
--- 30.7% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 32,087 (90,157 total cases)
--- 4.0% less cases per 100k residents than South Carolina
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Bill Fitzpatrick // Wikimedia Commons

#22. Bamberg County

- Population that is fully vaccinated: 52.4% (7,372 fully vaccinated)
--- 32.0% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 540 (76 total deaths)
--- 49.6% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 28,935 (4,070 total cases)
--- 13.5% less cases per 100k residents than South Carolina
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NatalieMaynor // Wikimedia Commons

#21. Newberry County

- Population that is fully vaccinated: 54.1% (20,793 fully vaccinated)
--- 29.8% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 539 (207 total deaths)
--- 49.3% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 40,023 (15,385 total cases)
--- 19.7% more cases per 100k residents than South Carolina
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Itsbrandoyo // Wikimedia Commons

#20. Berkeley County

- Population that is fully vaccinated: 54.2% (123,553 fully vaccinated)
--- 29.7% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 203 (462 total deaths)
--- 43.8% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 27,467 (62,599 total cases)
--- 17.9% less cases per 100k residents than South Carolina
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Lazyksaw // Wikimedia Commons

#19. Dorchester County

- Population that is fully vaccinated: 55.1% (89,725 fully vaccinated)
--- 28.5% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 324 (527 total deaths)
--- 10.2% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 40,773 (66,382 total cases)
--- 21.9% more cases per 100k residents than South Carolina
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#18. Georgetown County

- Population that is fully vaccinated: 56.0% (35,110 fully vaccinated)
--- 27.4% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 377 (236 total deaths)
--- 4.4% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 29,676 (18,601 total cases)
--- 11.3% less cases per 100k residents than South Carolina
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Robert Thomas Mckenzie Jr // Wikimedia Commons

#17. Florence County

- Population that is fully vaccinated: 56.5% (78,132 fully vaccinated)
--- 26.7% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 482 (666 total deaths)
--- 33.5% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 34,770 (48,085 total cases)
--- 4.0% more cases per 100k residents than South Carolina
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#16. Greenville County

- Population that is fully vaccinated: 57.2% (299,312 fully vaccinated)
--- 25.8% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 395 (2,067 total deaths)
--- 9.4% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 37,387 (195,737 total cases)
--- 11.8% more cases per 100k residents than South Carolina
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Ralph Hightower // Wikimedia Commons

#15. Lexington County

- Population that is fully vaccinated: 57.4% (171,343 fully vaccinated)
--- 25.6% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 308 (920 total deaths)
--- 14.7% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 38,427 (114,801 total cases)
--- 14.9% more cases per 100k residents than South Carolina
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Ammodramus // Wikimedia Commons

#14. Orangeburg County

- Population that is fully vaccinated: 57.6% (49,626 fully vaccinated)
--- 25.3% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 499 (430 total deaths)
--- 38.2% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 32,272 (27,810 total cases)
--- 3.5% less cases per 100k residents than South Carolina
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Calvin Beale // Wikimedia Commons

#13. Barnwell County

- Population that is fully vaccinated: 57.7% (12,034 fully vaccinated)
--- 25.2% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 498 (104 total deaths)
--- 38.0% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 31,118 (6,493 total cases)
--- 6.9% less cases per 100k residents than South Carolina
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Pollinator // Wikimedia Commons

#12. Horry County

- Population that is fully vaccinated: 58.3% (206,578 fully vaccinated)
--- 24.4% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 348 (1,231 total deaths)
--- 3.6% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 32,324 (114,454 total cases)
--- 3.3% less cases per 100k residents than South Carolina
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Pollinator // Wikimedia Commons

#11. Williamsburg County

- Population that is fully vaccinated: 58.6% (17,800 fully vaccinated)
--- 24.0% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 494 (150 total deaths)
--- 36.8% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 32,083 (9,743 total cases)
--- 4.1% less cases per 100k residents than South Carolina
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Pollinator // Wikimedia Commons

#10. Sumter County

- Population that is fully vaccinated: 58.6% (62,569 fully vaccinated)
--- 24.0% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 389 (415 total deaths)
--- 7.8% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 30,994 (33,077 total cases)
--- 7.3% less cases per 100k residents than South Carolina
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Pollinator // Wikimedia Commons

#9. Kershaw County

- Population that is fully vaccinated: 60.6% (40,310 fully vaccinated)
--- 21.4% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 407 (271 total deaths)
--- 12.7% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 38,588 (25,681 total cases)
--- 15.4% more cases per 100k residents than South Carolina
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Upstateherd // Wikimedia Commons

#8. Allendale County

- Population that is fully vaccinated: 60.7% (5,272 fully vaccinated)
--- 21.3% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 276 (24 total deaths)
--- 23.5% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 27,060 (2,351 total cases)
--- 19.1% less cases per 100k residents than South Carolina
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Farrargirl // Wikimedia Commons

#7. McCormick County

- Population that is fully vaccinated: 60.7% (5,743 fully vaccinated)
--- 21.3% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 423 (40 total deaths)
--- 17.2% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 27,158 (2,570 total cases)
--- 18.8% less cases per 100k residents than South Carolina
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Upstateherd // Wikimedia Commons

#6. Edgefield County

- Population that is fully vaccinated: 62.5% (17,044 fully vaccinated)
--- 18.9% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 268 (73 total deaths)
--- 25.8% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 28,613 (7,800 total cases)
--- 14.4% less cases per 100k residents than South Carolina
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#5. Richland County

- Population that is fully vaccinated: 62.9% (261,344 fully vaccinated)
--- 18.4% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 238 (989 total deaths)
--- 34.1% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 36,105 (150,109 total cases)
--- 8.0% more cases per 100k residents than South Carolina
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Ffuhr // Wikimedia Commons

#4. Hampton County

- Population that is fully vaccinated: 65.7% (12,621 fully vaccinated)
--- 14.8% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 447 (86 total deaths)
--- 23.8% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 29,596 (5,689 total cases)
--- 11.5% less cases per 100k residents than South Carolina
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Upstateherd // Wikimedia Commons

#3. Fairfield County

- Population that is fully vaccinated: 67.0% (14,962 fully vaccinated)
--- 13.1% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 497 (111 total deaths)
--- 37.7% more deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 31,651 (7,073 total cases)
--- 5.3% less cases per 100k residents than South Carolina
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#2. Charleston County

- Population that is fully vaccinated: 67.8% (279,045 fully vaccinated)
--- 12.1% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 240 (988 total deaths)
--- 33.5% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 32,008 (131,683 total cases)
--- 4.3% less cases per 100k residents than South Carolina
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#1. Beaufort County

- Population that is fully vaccinated: 70.3% (135,030 fully vaccinated)
--- 8.8% lower vaccination rate than South Carolina
- Cumulative deaths per 100k: 208 (400 total deaths)
--- 42.4% less deaths per 100k residents than South Carolina
- Cumulative cases per 100k: 26,404 (50,728 total cases)
--- 21.0% less cases per 100k residents than South Carolina

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