The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.
The United States as of Oct. 28 reached over 1 million COVID-19-related deaths and 97.4 million COVID-19 cases, according to Johns Hopkins University. Currently, 68.4% of the population is fully vaccinated, and 7.3% of people have received the most recent bivalent booster dose.
Stacker compiled a list of the counties with highest COVID-19 vaccination rates in Missouri using data from the U.S. Department of Health & Human Services and Covid Act Now. Counties are ranked by the highest vaccination rate as of Oct. 27, 2022. Due to inconsistencies in reporting, some counties do not have vaccination data available. Case count data based on Oct. 13 numbers reported by the Department of Health and Human Services. Keep reading to see whether your county ranks among the highest COVID-19 vaccination rates in your state.
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#50. Marion County
- Population that is fully vaccinated: 43.1% (12,301 fully vaccinated)
--- 24.1% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 452 (129 total deaths)
--- 27.0% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 32,240 (9,198 total cases)
--- 18.2% more cases per 100k residents than Missouri
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#49. Holt County
- Population that is fully vaccinated: 43.2% (1,902 fully vaccinated)
--- 23.9% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 704 (31 total deaths)
--- 97.8% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,640 (1,217 total cases)
--- 1.4% more cases per 100k residents than Missouri
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#48. Webster County
- Population that is fully vaccinated: 43.2% (17,117 fully vaccinated)
--- 23.9% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 404 (160 total deaths)
--- 13.5% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 24,932 (9,871 total cases)
--- 8.6% less cases per 100k residents than Missouri
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#47. Livingston County
- Population that is fully vaccinated: 43.9% (6,690 fully vaccinated)
--- 22.7% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 676 (103 total deaths)
--- 89.9% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,497 (4,187 total cases)
--- 0.8% more cases per 100k residents than Missouri
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#46. Mississippi County
- Population that is fully vaccinated: 44.0% (5,800 fully vaccinated)
--- 22.5% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 478 (63 total deaths)
--- 34.3% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 32,109 (4,232 total cases)
--- 17.8% more cases per 100k residents than Missouri
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6 / 50
#45. Sullivan County
- Population that is fully vaccinated: 44.1% (2,688 fully vaccinated)
--- 22.4% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 411 (25 total deaths)
--- 15.4% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 31,483 (1,917 total cases)
--- 15.5% more cases per 100k residents than Missouri
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#44. Howard County
- Population that is fully vaccinated: 44.2% (4,418 fully vaccinated)
--- 22.2% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 320 (32 total deaths)
--- 10.1% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 28,177 (2,818 total cases)
--- 3.3% more cases per 100k residents than Missouri
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#43. Pettis County
- Population that is fully vaccinated: 44.2% (18,704 fully vaccinated)
--- 22.2% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 423 (179 total deaths)
--- 18.8% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 33,421 (14,150 total cases)
--- 22.6% more cases per 100k residents than Missouri
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#42. Dade County
- Population that is fully vaccinated: 44.4% (3,360 fully vaccinated)
--- 21.8% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 608 (46 total deaths)
--- 70.8% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 22,259 (1,683 total cases)
--- 18.4% less cases per 100k residents than Missouri
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#41. Scott County
- Population that is fully vaccinated: 44.5% (17,028 fully vaccinated)
--- 21.7% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 439 (168 total deaths)
--- 23.3% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 34,193 (13,089 total cases)
--- 25.4% more cases per 100k residents than Missouri
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#40. St. Francois County
- Population that is fully vaccinated: 44.7% (30,018 fully vaccinated)
--- 21.3% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 470 (316 total deaths)
--- 32.0% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 32,944 (22,143 total cases)
--- 20.8% more cases per 100k residents than Missouri
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#39. Maries County
- Population that is fully vaccinated: 45.1% (3,925 fully vaccinated)
--- 20.6% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 460 (40 total deaths)
--- 29.2% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 21,421 (1,863 total cases)
--- 21.4% less cases per 100k residents than Missouri
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#38. Phelps County
- Population that is fully vaccinated: 45.1% (20,101 fully vaccinated)
--- 20.6% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 563 (251 total deaths)
--- 58.1% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,088 (12,074 total cases)
--- 0.7% less cases per 100k residents than Missouri
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#37. Gentry County
- Population that is fully vaccinated: 45.3% (2,974 fully vaccinated)
--- 20.2% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 533 (35 total deaths)
--- 49.7% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 37,863 (2,488 total cases)
--- 38.9% more cases per 100k residents than Missouri
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#36. Monroe County
- Population that is fully vaccinated: 45.6% (3,945 fully vaccinated)
--- 19.7% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 578 (50 total deaths)
--- 62.4% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 28,008 (2,421 total cases)
--- 2.7% more cases per 100k residents than Missouri
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#35. Barry County
- Population that is fully vaccinated: 45.8% (16,389 fully vaccinated)
--- 19.4% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 416 (149 total deaths)
--- 16.9% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 21,065 (7,539 total cases)
--- 22.7% less cases per 100k residents than Missouri
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#34. Cooper County
- Population that is fully vaccinated: 45.9% (8,127 fully vaccinated)
--- 19.2% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 452 (80 total deaths)
--- 27.0% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 25,750 (4,560 total cases)
--- 5.6% less cases per 100k residents than Missouri
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#33. Ste. Genevieve County
- Population that is fully vaccinated: 45.9% (8,214 fully vaccinated)
--- 19.2% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 224 (40 total deaths)
--- 37.1% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 24,690 (4,418 total cases)
--- 9.5% less cases per 100k residents than Missouri
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#32. Johnson County
- Population that is fully vaccinated: 46.2% (24,963 fully vaccinated)
--- 18.7% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 277 (150 total deaths)
--- 22.2% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 25,671 (13,878 total cases)
--- 5.9% less cases per 100k residents than Missouri
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#31. Jefferson County
- Population that is fully vaccinated: 46.2% (103,970 fully vaccinated)
--- 18.7% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 309 (696 total deaths)
--- 13.2% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 28,300 (63,698 total cases)
--- 3.8% more cases per 100k residents than Missouri
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#30. Camden County
- Population that is fully vaccinated: 46.8% (21,681 fully vaccinated)
--- 17.6% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 412 (191 total deaths)
--- 15.7% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 22,557 (10,445 total cases)
--- 17.3% less cases per 100k residents than Missouri
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#29. Lafayette County
- Population that is fully vaccinated: 47.0% (15,364 fully vaccinated)
--- 17.3% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 434 (142 total deaths)
--- 21.9% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 26,752 (8,750 total cases)
--- 1.9% less cases per 100k residents than Missouri
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#28. Adair County
- Population that is fully vaccinated: 47.1% (11,940 fully vaccinated)
--- 17.1% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 272 (69 total deaths)
--- 23.6% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 25,060 (6,351 total cases)
--- 8.1% less cases per 100k residents than Missouri
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#27. Christian County
- Population that is fully vaccinated: 47.2% (41,817 fully vaccinated)
--- 16.9% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 312 (276 total deaths)
--- 12.4% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 26,746 (23,696 total cases)
--- 1.9% less cases per 100k residents than Missouri
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#26. Henry County
- Population that is fully vaccinated: 47.3% (10,318 fully vaccinated)
--- 16.7% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 417 (91 total deaths)
--- 17.1% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 30,654 (6,690 total cases)
--- 12.4% more cases per 100k residents than Missouri
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26 / 50
#25. Saline County
- Population that is fully vaccinated: 47.7% (10,865 fully vaccinated)
--- 16.0% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 501 (114 total deaths)
--- 40.7% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 30,776 (7,005 total cases)
--- 12.9% more cases per 100k residents than Missouri
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#24. Linn County
- Population that is fully vaccinated: 47.8% (5,699 fully vaccinated)
--- 15.8% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 587 (70 total deaths)
--- 64.9% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 24,597 (2,932 total cases)
--- 9.8% less cases per 100k residents than Missouri
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#23. Shelby County
- Population that is fully vaccinated: 47.9% (2,841 fully vaccinated)
--- 15.7% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 253 (15 total deaths)
--- 28.9% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 32,530 (1,929 total cases)
--- 19.3% more cases per 100k residents than Missouri
29 / 50
#22. Jasper County
- Population that is fully vaccinated: 48.7% (59,099 fully vaccinated)
--- 14.3% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 462 (561 total deaths)
--- 29.8% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 31,796 (38,578 total cases)
--- 16.6% more cases per 100k residents than Missouri
30 / 50
#21. Clinton County
- Population that is fully vaccinated: 49.2% (10,025 fully vaccinated)
--- 13.4% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 613 (125 total deaths)
--- 72.2% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 26,757 (5,455 total cases)
--- 1.9% less cases per 100k residents than Missouri
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31 / 50
#20. Callaway County
- Population that is fully vaccinated: 49.4% (22,108 fully vaccinated)
--- 13.0% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 317 (142 total deaths)
--- 11.0% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 30,704 (13,738 total cases)
--- 12.6% more cases per 100k residents than Missouri
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#19. Benton County
- Population that is fully vaccinated: 49.5% (9,631 fully vaccinated)
--- 12.9% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 566 (110 total deaths)
--- 59.0% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 26,153 (5,085 total cases)
--- 4.1% less cases per 100k residents than Missouri
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#18. Montgomery County
- Population that is fully vaccinated: 49.9% (5,762 fully vaccinated)
--- 12.1% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 528 (61 total deaths)
--- 48.3% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 25,037 (2,892 total cases)
--- 8.2% less cases per 100k residents than Missouri
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#17. Nodaway County
- Population that is fully vaccinated: 50.2% (11,095 fully vaccinated)
--- 11.6% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 226 (50 total deaths)
--- 36.5% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 31,717 (7,007 total cases)
--- 16.3% more cases per 100k residents than Missouri
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#16. Cape Girardeau County
- Population that is fully vaccinated: 50.3% (39,686 fully vaccinated)
--- 11.4% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 325 (256 total deaths)
--- 8.7% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,967 (22,058 total cases)
--- 2.6% more cases per 100k residents than Missouri
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36 / 50
#15. Carroll County
- Population that is fully vaccinated: 50.5% (4,385 fully vaccinated)
--- 11.1% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 530 (46 total deaths)
--- 48.9% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 28,771 (2,497 total cases)
--- 5.5% more cases per 100k residents than Missouri
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#14. Greene County
- Population that is fully vaccinated: 50.8% (148,988 fully vaccinated)
--- 10.6% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 377 (1,104 total deaths)
--- 5.9% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,485 (80,554 total cases)
--- 0.8% more cases per 100k residents than Missouri
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#13. Gasconade County
- Population that is fully vaccinated: 51.6% (7,586 fully vaccinated)
--- 9.2% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 721 (106 total deaths)
--- 102.5% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 26,003 (3,824 total cases)
--- 4.6% less cases per 100k residents than Missouri
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#12. Cass County
- Population that is fully vaccinated: 54.2% (57,288 fully vaccinated)
--- 4.6% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 317 (335 total deaths)
--- 11.0% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,118 (28,685 total cases)
--- 0.6% less cases per 100k residents than Missouri
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#11. Cole County
- Population that is fully vaccinated: 54.3% (41,681 fully vaccinated)
--- 4.4% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 386 (296 total deaths)
--- 8.4% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 29,453 (22,604 total cases)
--- 8.0% more cases per 100k residents than Missouri
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41 / 50
#10. Franklin County
- Population that is fully vaccinated: 55.5% (57,661 fully vaccinated)
--- 2.3% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 379 (394 total deaths)
--- 6.5% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 28,417 (29,544 total cases)
--- 4.2% more cases per 100k residents than Missouri
42 / 50
#9. Clay County
- Population that is fully vaccinated: 56.0% (140,088 fully vaccinated)
--- 1.4% lower vaccination rate than Missouri
- Cumulative deaths per 100k: 156 (391 total deaths)
--- 56.2% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 12,611 (31,520 total cases)
--- 53.8% less cases per 100k residents than Missouri
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#8. Atchison County
- Population that is fully vaccinated: 57.7% (2,967 fully vaccinated)
--- 1.6% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 467 (24 total deaths)
--- 31.2% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 32,005 (1,646 total cases)
--- 17.4% more cases per 100k residents than Missouri
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#7. Platte County
- Population that is fully vaccinated: 59.2% (61,855 fully vaccinated)
--- 4.2% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 102 (106 total deaths)
--- 71.3% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 11,566 (12,077 total cases)
--- 57.6% less cases per 100k residents than Missouri
45 / 50
#6. Jackson County
- Population that is fully vaccinated: 59.8% (420,128 fully vaccinated)
--- 5.3% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 376 (2,644 total deaths)
--- 5.6% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 34,986 (245,953 total cases)
--- 28.3% more cases per 100k residents than Missouri
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46 / 50
#5. Pulaski County
- Population that is fully vaccinated: 59.9% (31,514 fully vaccinated)
--- 5.5% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 238 (125 total deaths)
--- 33.1% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 19,672 (10,349 total cases)
--- 27.9% less cases per 100k residents than Missouri
47 / 50
#4. St. Louis city
- Population that is fully vaccinated: 62.1% (186,606 fully vaccinated)
--- 9.3% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 274 (825 total deaths)
--- 23.0% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 23,677 (71,168 total cases)
--- 13.2% less cases per 100k residents than Missouri
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#3. St. Charles County
- Population that is fully vaccinated: 63.2% (254,150 fully vaccinated)
--- 11.3% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 248 (999 total deaths)
--- 30.3% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,926 (112,268 total cases)
--- 2.4% more cases per 100k residents than Missouri
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#2. Boone County
- Population that is fully vaccinated: 64.3% (115,985 fully vaccinated)
--- 13.2% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 152 (275 total deaths)
--- 57.3% less deaths per 100k residents than Missouri
- Cumulative cases per 100k: 28,005 (50,539 total cases)
--- 2.7% more cases per 100k residents than Missouri
50 / 50
#1. St. Louis County
- Population that is fully vaccinated: 67.0% (665,789 fully vaccinated)
--- 18.0% higher vaccination rate than Missouri
- Cumulative deaths per 100k: 358 (3,559 total deaths)
--- 0.6% more deaths per 100k residents than Missouri
- Cumulative cases per 100k: 27,651 (274,912 total cases)
--- 1.4% more cases per 100k residents than Missouri
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