Counties where the most opioids are dispensed in Illinois

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When Purdue Pharma first began sales of OxyContin in the late 1990s, it was advertised as relief for cancer patients and people with chronic pain. Aggressive marketing fueled the drug's popularity, along with that of other opioid pain management drugs on the market. But as the company touted OxyContin to physicians, it downplayed the drug's addictiveness, according to confidential Justice Department reports obtained by news organizations, leading to widespread use that has fueled an opioid epidemic across the U.S.

More than 645,000 people have died from opioid-related overdoses between 1999 and 2021, according to the Centers for Disease Control and Prevention. Provisional data shows just under 80,000 people died in 2022 alone.

Opioid prescriptions have decreased dramatically over the past decade as physicians and public health officials learned about the dangers of OxyContin and other opioids prescribed for pain management. In 2020, the most recent year with data available, the national opioid dispense rate reached 43.3 per 100 people, the lowest rate ever recorded.

A 2022 study funded by the National Institute on Drug Abuse found that counties with higher dispensing rates had more cases of opioid misuse and dependence. The study suggested that reducing prescriptions at the local level can lower a community's rate of opioid abuse or misuse.

Other studies, however, have suggested that decreasing prescriptions may have fueled a new phase of the opioid epidemic: the rise of synthetics like fentanyl. In 2020, synthetics accounted for 82% of all opioid deaths.

It's also important to note that, as awareness has grown about the dangers of dispensing opioid prescription painkillers, more health care professionals are also prescribing medications like Suboxone–which contains buprenorphine and naloxone—for the treatment of addiction and opioid use disorders. While Suboxone is also an opioid medication, it works differently than typical opioid painkillers, blocking the effects of more powerful and addictive opioids to deter intentional misuse.

Using data from the Centers for Disease Control and Prevention, Ophelia broke down counties in every state with the highest opioid dispense rates. In the case of a tie, the county with the higher population and higher raw number is ranked higher. Data was available for 98% of counties in the United States. Overall in Illinois, the opioid dispensing rate was 40.2 per 100 people, compared to 43.3 nationally.

Read the national story for additional historical context and see where other counties outside of Illinois stand.

#50. Lake County

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#50. Lake County

- Opioid dispensing rate: 35.0 per 100 people
--- 12.9% lower than state average
--- 19.2% lower than national average

#49. Edgar County

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#49. Edgar County

- Opioid dispensing rate: 35.1 per 100 people
--- 12.7% lower than state average
--- 18.9% lower than national average

#48. Wabash County

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#48. Wabash County

- Opioid dispensing rate: 35.7 per 100 people
--- 11.2% lower than state average
--- 17.6% lower than national average

#47. Greene County

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#47. Greene County

- Opioid dispensing rate: 36.1 per 100 people
--- 10.2% lower than state average
--- 16.6% lower than national average

#46. Cook County

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#46. Cook County

- Opioid dispensing rate: 36.1 per 100 people
--- 10.2% lower than state average
--- 16.6% lower than national average

#45. Putnam County

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#45. Putnam County

- Opioid dispensing rate: 36.5 per 100 people
--- 9.2% lower than state average
--- 15.7% lower than national average

#44. Edwards County

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#44. Edwards County

- Opioid dispensing rate: 36.9 per 100 people
--- 8.2% lower than state average
--- 14.8% lower than national average

#43. Iroquois County

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#43. Iroquois County

- Opioid dispensing rate: 36.9 per 100 people
--- 8.2% lower than state average
--- 14.8% lower than national average

#42. Randolph County

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#42. Randolph County

- Opioid dispensing rate: 39.1 per 100 people
--- 2.7% lower than state average
--- 9.7% lower than national average

#41. Pike County

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#41. Pike County

- Opioid dispensing rate: 41.0 per 100 people
--- 2.0% higher than state average
--- 5.3% lower than national average

#40. Richland County

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#40. Richland County

- Opioid dispensing rate: 41.9 per 100 people
--- 4.2% higher than state average
--- 3.2% lower than national average

#39. Brown County

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#39. Brown County

- Opioid dispensing rate: 42.5 per 100 people
--- 5.7% higher than state average
--- 1.8% lower than national average

#38. Lawrence County

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#38. Lawrence County

- Opioid dispensing rate: 42.5 per 100 people
--- 5.7% higher than state average
--- 1.8% lower than national average

#37. Dupage County

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#37. Dupage County

- Opioid dispensing rate: 43.0 per 100 people
--- 7.0% higher than state average
--- 0.7% lower than national average

#36. Livingston County

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#36. Livingston County

- Opioid dispensing rate: 44.0 per 100 people
--- 9.5% higher than state average
--- 1.6% higher than national average

#35. Rock Island County

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#35. Rock Island County

- Opioid dispensing rate: 46.1 per 100 people
--- 14.7% higher than state average
--- 6.5% higher than national average

#34. Champaign County

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#34. Champaign County

- Opioid dispensing rate: 46.6 per 100 people
--- 15.9% higher than state average
--- 7.6% higher than national average

#33. Grundy County

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#33. Grundy County

- Opioid dispensing rate: 47.1 per 100 people
--- 17.2% higher than state average
--- 8.8% higher than national average

#32. Montgomery County

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#32. Montgomery County

- Opioid dispensing rate: 49.1 per 100 people
--- 22.1% higher than state average
--- 13.4% higher than national average

#31. Mcdonough County

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#31. Mcdonough County

- Opioid dispensing rate: 49.4 per 100 people
--- 22.9% higher than state average
--- 14.1% higher than national average

#30. Fulton County

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#30. Fulton County

- Opioid dispensing rate: 49.5 per 100 people
--- 23.1% higher than state average
--- 14.3% higher than national average

#29. Stephenson County

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#29. Stephenson County

- Opioid dispensing rate: 49.6 per 100 people
--- 23.4% higher than state average
--- 14.5% higher than national average

#28. Clark County

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#28. Clark County

- Opioid dispensing rate: 49.9 per 100 people
--- 24.1% higher than state average
--- 15.2% higher than national average

#27. Vermilion County

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#27. Vermilion County

- Opioid dispensing rate: 50.2 per 100 people
--- 24.9% higher than state average
--- 15.9% higher than national average

#26. Mclean County

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#26. Mclean County

- Opioid dispensing rate: 50.9 per 100 people
--- 26.6% higher than state average
--- 17.6% higher than national average

#25. Bureau County

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#25. Bureau County

- Opioid dispensing rate: 51.6 per 100 people
--- 28.4% higher than state average
--- 19.2% higher than national average

#24. Saint Clair County

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#24. Saint Clair County

- Opioid dispensing rate: 53.1 per 100 people
--- 32.1% higher than state average
--- 22.6% higher than national average

#23. Morgan County

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#23. Morgan County

- Opioid dispensing rate: 53.6 per 100 people
--- 33.3% higher than state average
--- 23.8% higher than national average

#22. Madison County

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#22. Madison County

- Opioid dispensing rate: 54.6 per 100 people
--- 35.8% higher than state average
--- 26.1% higher than national average

#21. Kankakee County

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#21. Kankakee County

- Opioid dispensing rate: 55.1 per 100 people
--- 37.1% higher than state average
--- 27.3% higher than national average

#20. Marion County

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#20. Marion County

- Opioid dispensing rate: 55.5 per 100 people
--- 38.1% higher than state average
--- 28.2% higher than national average

#19. Alexander County

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#19. Alexander County

- Opioid dispensing rate: 56.0 per 100 people
--- 39.3% higher than state average
--- 29.3% higher than national average

#18. Wayne County

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#18. Wayne County

- Opioid dispensing rate: 56.2 per 100 people
--- 39.8% higher than state average
--- 29.8% higher than national average

#17. Perry County

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#17. Perry County

- Opioid dispensing rate: 59.3 per 100 people
--- 47.5% higher than state average
--- 37.0% higher than national average

#16. Coles County

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#16. Coles County

- Opioid dispensing rate: 61.9 per 100 people
--- 54.0% higher than state average
--- 43.0% higher than national average

#15. Effingham County

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#15. Effingham County

- Opioid dispensing rate: 63.3 per 100 people
--- 57.5% higher than state average
--- 46.2% higher than national average

#14. Knox County

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#14. Knox County

- Opioid dispensing rate: 63.3 per 100 people
--- 57.5% higher than state average
--- 46.2% higher than national average

#13. Winnebago County

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#13. Winnebago County

- Opioid dispensing rate: 66.2 per 100 people
--- 64.7% higher than state average
--- 52.9% higher than national average

#12. Jersey County

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#12. Jersey County

- Opioid dispensing rate: 68.3 per 100 people
--- 69.9% higher than state average
--- 57.7% higher than national average

#11. Union County

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#11. Union County

- Opioid dispensing rate: 69.2 per 100 people
--- 72.1% higher than state average
--- 59.8% higher than national average

#10. Macon County

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#10. Macon County

- Opioid dispensing rate: 70.9 per 100 people
--- 76.4% higher than state average
--- 63.7% higher than national average

#9. Sangamon County

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#9. Sangamon County

- Opioid dispensing rate: 84.9 per 100 people
--- 111.2% higher than state average
--- 96.1% higher than national average

#8. Massac County

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#8. Massac County

- Opioid dispensing rate: 86.3 per 100 people
--- 114.7% higher than state average
--- 99.3% higher than national average

#7. Williamson County

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#7. Williamson County

- Opioid dispensing rate: 90.0 per 100 people
--- 123.9% higher than state average
--- 107.9% higher than national average

#6. Adams County

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#6. Adams County

- Opioid dispensing rate: 91.4 per 100 people
--- 127.4% higher than state average
--- 111.1% higher than national average

#5. Jefferson County

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#5. Jefferson County

- Opioid dispensing rate: 96.1 per 100 people
--- 139.1% higher than state average
--- 121.9% higher than national average

#4. Jackson County

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#4. Jackson County

- Opioid dispensing rate: 98.3 per 100 people
--- 144.5% higher than state average
--- 127.0% higher than national average

#3. Peoria County

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#3. Peoria County

- Opioid dispensing rate: 98.8 per 100 people
--- 145.8% higher than state average
--- 128.2% higher than national average

#2. Saline County

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#2. Saline County

- Opioid dispensing rate: 129.7 per 100 people
--- 222.6% higher than state average
--- 199.5% higher than national average

#1. Hardin County

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#1. Hardin County

- Opioid dispensing rate: 159.5 per 100 people
--- 296.8% higher than state average
--- 268.4% higher than national average