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1 / 50#50. Lawrence County
- Opioid dispensing rate: 35.7 per 100 people
--- 34.4% lower than state average
--- 17.6% lower than national average
Counties where the most opioids are dispensed in Missouri
When Purdue Pharma first began sales of OxyContin in the late 1990s, it was advertised as relief for cancer patients and people with chronic pain. Aggressive marketing fueled the drug's popularity, along with that of other opioid pain management drugs on the market. But as the company touted OxyContin to physicians, it downplayed the drug's addictiveness, according to confidential Justice Department reports obtained by news organizations, leading to widespread use that has fueled an opioid epidemic across the U.S.
More than 645,000 people have died from opioid-related overdoses between 1999 and 2021, according to the Centers for Disease Control and Prevention. Provisional data shows just under 80,000 people died in 2022 alone.
Opioid prescriptions have decreased dramatically over the past decade as physicians and public health officials learned about the dangers of OxyContin and other opioids prescribed for pain management. In 2020, the most recent year with data available, the national opioid dispense rate reached 43.3 per 100 people, the lowest rate ever recorded.
A 2022 study funded by the National Institute on Drug Abuse found that counties with higher dispensing rates had more cases of opioid misuse and dependence. The study suggested that reducing prescriptions at the local level can lower a community's rate of opioid abuse or misuse.
Other studies, however, have suggested that decreasing prescriptions may have fueled a new phase of the opioid epidemic: the rise of synthetics like fentanyl. In 2020, synthetics accounted for 82% of all opioid deaths.
It's also important to note that, as awareness has grown about the dangers of dispensing opioid prescription painkillers, more health care professionals are also prescribing medications like Suboxone–which contains buprenorphine and naloxone—for the treatment of addiction and opioid use disorders. While Suboxone is also an opioid medication, it works differently than typical opioid painkillers, blocking the effects of more powerful and addictive opioids to deter intentional misuse.
Using data from the Centers for Disease Control and Prevention, Ophelia broke down counties in every state with the highest opioid dispense rates. In the case of a tie, the county with the higher population and higher raw number is ranked higher. Data was available for 98% of counties in the United States. Overall in Missouri, the opioid dispensing rate was 54.4 per 100 people, compared to 43.3 nationally.
Read the national story for additional historical context and see where other counties outside of Missouri stand.
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2 / 50#49. Ray County
- Opioid dispensing rate: 36.0 per 100 people
--- 33.8% lower than state average
--- 16.9% lower than national average
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3 / 50#48. Laclede County
- Opioid dispensing rate: 36.4 per 100 people
--- 33.1% lower than state average
--- 15.9% lower than national average
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4 / 50#47. Platte County
- Opioid dispensing rate: 37.1 per 100 people
--- 31.8% lower than state average
--- 14.3% lower than national average
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5 / 50#46. Nodaway County
- Opioid dispensing rate: 37.8 per 100 people
--- 30.5% lower than state average
--- 12.7% lower than national average
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6 / 50#45. Stoddard County
- Opioid dispensing rate: 38.0 per 100 people
--- 30.1% lower than state average
--- 12.2% lower than national average
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7 / 50#44. Madison County
- Opioid dispensing rate: 38.8 per 100 people
--- 28.7% lower than state average
--- 10.4% lower than national average
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8 / 50#43. Daviess County
- Opioid dispensing rate: 39.1 per 100 people
--- 28.1% lower than state average
--- 9.7% lower than national average
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9 / 50#42. Clark County
- Opioid dispensing rate: 39.2 per 100 people
--- 27.9% lower than state average
--- 9.5% lower than national average
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10 / 50#41. Ripley County
- Opioid dispensing rate: 39.5 per 100 people
--- 27.4% lower than state average
--- 8.8% lower than national average
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11 / 50#40. Pike County
- Opioid dispensing rate: 40.2 per 100 people
--- 26.1% lower than state average
--- 7.2% lower than national average
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12 / 50#39. Scotland County
- Opioid dispensing rate: 40.8 per 100 people
--- 25.0% lower than state average
--- 5.8% lower than national average
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13 / 50#38. Cass County
- Opioid dispensing rate: 41.6 per 100 people
--- 23.5% lower than state average
--- 3.9% lower than national average
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14 / 50#37. Saline County
- Opioid dispensing rate: 42.0 per 100 people
--- 22.8% lower than state average
--- 3.0% lower than national average
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15 / 50#36. Christian County
- Opioid dispensing rate: 45.4 per 100 people
--- 16.5% lower than state average
--- 4.8% higher than national average
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16 / 50#35. Webster County
- Opioid dispensing rate: 45.8 per 100 people
--- 15.8% lower than state average
--- 5.8% higher than national average
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17 / 50#34. Franklin County
- Opioid dispensing rate: 48.3 per 100 people
--- 11.2% lower than state average
--- 11.5% higher than national average
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18 / 50#33. Camden County
- Opioid dispensing rate: 49.7 per 100 people
--- 8.6% lower than state average
--- 14.8% higher than national average
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19 / 50#32. Carroll County
- Opioid dispensing rate: 49.8 per 100 people
--- 8.5% lower than state average
--- 15.0% higher than national average
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20 / 50#31. Clay County
- Opioid dispensing rate: 51.9 per 100 people
--- 4.6% lower than state average
--- 19.9% higher than national average
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21 / 50#30. Barry County
- Opioid dispensing rate: 53.2 per 100 people
--- 2.2% lower than state average
--- 22.9% higher than national average
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22 / 50#29. Buchanan County
- Opioid dispensing rate: 54.4 per 100 people
--- 0.0% lower than state average
--- 25.6% higher than national average
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23 / 50#28. Dent County
- Opioid dispensing rate: 54.9 per 100 people
--- 0.9% higher than state average
--- 26.8% higher than national average
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24 / 50#27. Lewis County
- Opioid dispensing rate: 55.0 per 100 people
--- 1.1% higher than state average
--- 27.0% higher than national average
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25 / 50#26. Dade County
- Opioid dispensing rate: 57.9 per 100 people
--- 6.4% higher than state average
--- 33.7% higher than national average
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26 / 50#25. Jackson County
- Opioid dispensing rate: 58.4 per 100 people
--- 7.4% higher than state average
--- 34.9% higher than national average
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27 / 50#24. Howard County
- Opioid dispensing rate: 59.3 per 100 people
--- 9.0% higher than state average
--- 37.0% higher than national average
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28 / 50#23. Polk County
- Opioid dispensing rate: 60.6 per 100 people
--- 11.4% higher than state average
--- 40.0% higher than national average
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29 / 50#22. Atchison County
- Opioid dispensing rate: 62.5 per 100 people
--- 14.9% higher than state average
--- 44.3% higher than national average
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30 / 50#21. Sullivan County
- Opioid dispensing rate: 63.2 per 100 people
--- 16.2% higher than state average
--- 46.0% higher than national average
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31 / 50#20. Cedar County
- Opioid dispensing rate: 63.2 per 100 people
--- 16.2% higher than state average
--- 46.0% higher than national average
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32 / 50#19. Mississippi County
- Opioid dispensing rate: 64.3 per 100 people
--- 18.2% higher than state average
--- 48.5% higher than national average
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33 / 50#18. Wright County
- Opioid dispensing rate: 65.3 per 100 people
--- 20.0% higher than state average
--- 50.8% higher than national average
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34 / 50#17. Cole County
- Opioid dispensing rate: 68.2 per 100 people
--- 25.4% higher than state average
--- 57.5% higher than national average
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35 / 50#16. Henry County
- Opioid dispensing rate: 68.7 per 100 people
--- 26.3% higher than state average
--- 58.7% higher than national average
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36 / 50#15. Taney County
- Opioid dispensing rate: 68.8 per 100 people
--- 26.5% higher than state average
--- 58.9% higher than national average
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37 / 50#14. Saint Louis County
- Opioid dispensing rate: 68.8 per 100 people
--- 26.5% higher than state average
--- 58.9% higher than national average
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38 / 50#13. Scott County
- Opioid dispensing rate: 70.6 per 100 people
--- 29.8% higher than state average
--- 63.0% higher than national average
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39 / 50#12. Dunklin County
- Opioid dispensing rate: 74.1 per 100 people
--- 36.2% higher than state average
--- 71.1% higher than national average
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40 / 50#11. Phelps County
- Opioid dispensing rate: 76.9 per 100 people
--- 41.4% higher than state average
--- 77.6% higher than national average
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41 / 50#10. Boone County
- Opioid dispensing rate: 80.3 per 100 people
--- 47.6% higher than state average
--- 85.5% higher than national average
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42 / 50#9. Saint Louis City
- Opioid dispensing rate: 80.7 per 100 people
--- 48.3% higher than state average
--- 86.4% higher than national average
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43 / 50#8. Greene County
- Opioid dispensing rate: 83.0 per 100 people
--- 52.6% higher than state average
--- 91.7% higher than national average
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44 / 50#7. Marion County
- Opioid dispensing rate: 83.6 per 100 people
--- 53.7% higher than state average
--- 93.1% higher than national average
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45 / 50#6. Adair County
- Opioid dispensing rate: 85.3 per 100 people
--- 56.8% higher than state average
--- 97.0% higher than national average
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46 / 50#5. Howell County
- Opioid dispensing rate: 93.7 per 100 people
--- 72.2% higher than state average
--- 116.4% higher than national average
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47 / 50#4. Jasper County
- Opioid dispensing rate: 95.8 per 100 people
--- 76.1% higher than state average
--- 121.2% higher than national average
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48 / 50#3. Saint Francois County
- Opioid dispensing rate: 99.5 per 100 people
--- 82.9% higher than state average
--- 129.8% higher than national average
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49 / 50#2. Cape Girardeau County
- Opioid dispensing rate: 102.8 per 100 people
--- 89.0% higher than state average
--- 137.4% higher than national average
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50 / 50#1. Butler County
- Opioid dispensing rate: 125.4 per 100 people
--- 130.5% higher than state average
--- 189.6% higher than national average
