Counties with highest COVID-19 infection rates in Illinois
The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.
Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely.
The United States as of Nov. 16 reached over 1 million COVID-19-related deaths and 98.1 million COVID-19 cases, according to Johns Hopkins University. Currently, 68.6% of the population is fully vaccinated, and 10.1% of vaccinated people have received the most recently available bivalent booster doses.
Stacker compiled a list of the counties with highest COVID-19 infection rates in Illinois using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to Nov. 10, 2022. Cumulative cases per 100,000 served as a tiebreaker.
Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.
#50. Perry County, IL
- Cumulative cases per 100k: 41,480 (8,676 total cases)
--- 37.1% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 473 (99 total deaths)
--- 49.7% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 51.6% (10,803 fully vaccinated)
#49. Macoupin County, IL
- Cumulative cases per 100k: 33,671 (15,127 total cases)
--- 11.3% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 323 (145 total deaths)
--- 2.2% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 56.0% (25,139 fully vaccinated)
#48. Jefferson County, IL
- Cumulative cases per 100k: 34,176 (12,879 total cases)
--- 13.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 478 (180 total deaths)
--- 51.3% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 48.4% (18,223 fully vaccinated)
#47. Williamson County, IL
- Cumulative cases per 100k: 40,780 (27,158 total cases)
--- 34.8% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 399 (266 total deaths)
--- 26.3% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 57.1% (38,035 fully vaccinated)
#46. DeKalb County, IL
- Cumulative cases per 100k: 28,733 (30,140 total cases)
--- 5.0% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 194 (204 total deaths)
--- 38.6% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 57.9% (60,687 fully vaccinated)
#45. Cook County, IL
- Cumulative cases per 100k: 27,858 (1,434,735 total cases)
--- 7.9% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 290 (14,915 total deaths)
--- 8.2% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 74.8% (3,850,252 fully vaccinated)
#44. Lake County, IL
- Cumulative cases per 100k: 28,174 (196,244 total cases)
--- 6.9% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 213 (1,485 total deaths)
--- 32.6% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 82.2% (572,490 fully vaccinated)
#43. McLean County, IL
- Cumulative cases per 100k: 35,599 (61,058 total cases)
--- 17.7% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 185 (318 total deaths)
--- 41.5% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 65.9% (113,069 fully vaccinated)
#42. Jersey County, IL
- Cumulative cases per 100k: 34,212 (7,449 total cases)
--- 13.1% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 349 (76 total deaths)
--- 10.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 57.1% (12,430 fully vaccinated)
#41. Adams County, IL
- Cumulative cases per 100k: 40,017 (26,185 total cases)
--- 32.3% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 341 (223 total deaths)
--- 7.9% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 53.5% (34,995 fully vaccinated)
#40. Marion County, IL
- Cumulative cases per 100k: 37,197 (13,839 total cases)
--- 23.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 589 (219 total deaths)
--- 86.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 46.8% (17,429 fully vaccinated)
#39. Knox County, IL
- Cumulative cases per 100k: 30,437 (15,127 total cases)
--- 0.6% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 463 (230 total deaths)
--- 46.5% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 60.6% (30,096 fully vaccinated)
#38. Kankakee County, IL
- Cumulative cases per 100k: 31,365 (34,458 total cases)
--- 3.7% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 346 (380 total deaths)
--- 9.5% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 53.7% (59,034 fully vaccinated)
#37. Boone County, IL
- Cumulative cases per 100k: 31,172 (16,691 total cases)
--- 3.1% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 228 (122 total deaths)
--- 27.8% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 62.8% (33,640 fully vaccinated)
#36. Livingston County, IL
- Cumulative cases per 100k: 35,071 (12,502 total cases)
--- 16.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 393 (140 total deaths)
--- 24.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 51.7% (18,428 fully vaccinated)
#35. Crawford County, IL
- Cumulative cases per 100k: 40,103 (7,486 total cases)
--- 32.6% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 257 (48 total deaths)
--- 18.7% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 52.4% (9,790 fully vaccinated)
#34. Washington County, IL
- Cumulative cases per 100k: 28,314 (3,932 total cases)
--- 6.4% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 259 (36 total deaths)
--- 18.0% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 59.6% (8,275 fully vaccinated)
#33. Iroquois County, IL
- Cumulative cases per 100k: 31,069 (8,424 total cases)
--- 2.7% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 472 (128 total deaths)
--- 49.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 52.2% (14,140 fully vaccinated)
#32. Kendall County, IL
- Cumulative cases per 100k: 30,495 (39,335 total cases)
--- 0.8% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 129 (167 total deaths)
--- 59.2% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 71.2% (91,779 fully vaccinated)
#31. Bond County, IL
- Cumulative cases per 100k: 30,513 (5,012 total cases)
--- 0.9% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 189 (31 total deaths)
--- 40.2% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 56.6% (9,296 fully vaccinated)
#30. De Witt County, IL
- Cumulative cases per 100k: 31,858 (4,982 total cases)
--- 5.3% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 262 (41 total deaths)
--- 17.1% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 54.1% (8,461 fully vaccinated)
#29. Ford County, IL
- Cumulative cases per 100k: 40,329 (5,227 total cases)
--- 33.3% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 532 (69 total deaths)
--- 68.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 59.0% (7,643 fully vaccinated)
#28. Schuyler County, IL
- Cumulative cases per 100k: 34,914 (2,363 total cases)
--- 15.4% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 251 (17 total deaths)
--- 20.6% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 56.7% (3,840 fully vaccinated)
#27. Lawrence County, IL
- Cumulative cases per 100k: 41,083 (6,441 total cases)
--- 35.8% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 287 (45 total deaths)
--- 9.2% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 41.9% (6,576 fully vaccinated)
#26. Montgomery County, IL
- Cumulative cases per 100k: 40,181 (11,417 total cases)
--- 32.8% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 384 (109 total deaths)
--- 21.5% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 52.4% (14,896 fully vaccinated)
#25. Lee County, IL
- Cumulative cases per 100k: 31,482 (10,734 total cases)
--- 4.1% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 249 (85 total deaths)
--- 21.2% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 61.2% (20,859 fully vaccinated)
#24. Tazewell County, IL
- Cumulative cases per 100k: 33,038 (43,545 total cases)
--- 9.2% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 373 (492 total deaths)
--- 18.0% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 60.5% (79,707 fully vaccinated)
#23. Peoria County, IL
- Cumulative cases per 100k: 31,513 (56,465 total cases)
--- 4.2% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 310 (556 total deaths)
--- 1.9% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 63.1% (113,101 fully vaccinated)
#22. Grundy County, IL
- Cumulative cases per 100k: 29,939 (15,285 total cases)
--- 1.0% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 284 (145 total deaths)
--- 10.1% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 59.1% (30,179 fully vaccinated)
#21. Macon County, IL
- Cumulative cases per 100k: 35,880 (37,318 total cases)
--- 18.6% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 348 (362 total deaths)
--- 10.1% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 54.5% (56,696 fully vaccinated)
#20. Morgan County, IL
- Cumulative cases per 100k: 34,334 (11,556 total cases)
--- 13.5% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 398 (134 total deaths)
--- 25.9% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 55.8% (18,786 fully vaccinated)
#19. Jasper County, IL
- Cumulative cases per 100k: 32,112 (3,086 total cases)
--- 6.2% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 333 (32 total deaths)
--- 5.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 42.7% (4,103 fully vaccinated)
#18. Saline County, IL
- Cumulative cases per 100k: 41,578 (9,767 total cases)
--- 37.5% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 447 (105 total deaths)
--- 41.5% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 49.9% (11,731 fully vaccinated)
#17. Jo Daviess County, IL
- Cumulative cases per 100k: 22,990 (4,882 total cases)
--- 24.0% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 207 (44 total deaths)
--- 34.5% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 81.4% (17,290 fully vaccinated)
#16. Stephenson County, IL
- Cumulative cases per 100k: 31,667 (14,091 total cases)
--- 4.7% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 393 (175 total deaths)
--- 24.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 62.7% (27,887 fully vaccinated)
#15. Winnebago County, IL
- Cumulative cases per 100k: 33,456 (94,536 total cases)
--- 10.6% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 308 (871 total deaths)
--- 2.5% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 59.9% (169,125 fully vaccinated)
#14. LaSalle County, IL
- Cumulative cases per 100k: 32,221 (35,014 total cases)
--- 6.5% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 372 (404 total deaths)
--- 17.7% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 59.8% (64,935 fully vaccinated)
#13. Edgar County, IL
- Cumulative cases per 100k: 36,000 (6,178 total cases)
--- 19.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 350 (60 total deaths)
--- 10.8% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 50.4% (8,643 fully vaccinated)
#12. Monroe County, IL
- Cumulative cases per 100k: 31,469 (10,900 total cases)
--- 4.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 387 (134 total deaths)
--- 22.5% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 64.1% (22,205 fully vaccinated)
#11. Moultrie County, IL
- Cumulative cases per 100k: 32,501 (4,713 total cases)
--- 7.5% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 345 (50 total deaths)
--- 9.2% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 45.1% (6,535 fully vaccinated)
#10. Brown County, IL
- Cumulative cases per 100k: 41,304 (2,717 total cases)
--- 36.6% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 258 (17 total deaths)
--- 18.4% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 54.4% (3,580 fully vaccinated)
#9. Marshall County, IL
- Cumulative cases per 100k: 28,912 (3,307 total cases)
--- 4.4% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 289 (33 total deaths)
--- 8.5% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 58.3% (6,665 fully vaccinated)
#8. Vermilion County, IL
- Cumulative cases per 100k: 43,861 (33,228 total cases)
--- 45.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 407 (308 total deaths)
--- 28.8% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 46.8% (35,490 fully vaccinated)
#7. Union County, IL
- Cumulative cases per 100k: 39,026 (6,499 total cases)
--- 29.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 402 (67 total deaths)
--- 27.2% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 58.4% (9,729 fully vaccinated)
#6. Sangamon County, IL
- Cumulative cases per 100k: 36,593 (71,236 total cases)
--- 21.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 217 (422 total deaths)
--- 31.3% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 66.9% (130,179 fully vaccinated)
#5. Pope County, IL
- Cumulative cases per 100k: 28,058 (1,172 total cases)
--- 7.2% less cases per 100k residents than Illinois
- Cumulative deaths per 100k: 215 (9 total deaths)
--- 32.0% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 40.3% (1,683 fully vaccinated)
#4. Pike County, IL
- Cumulative cases per 100k: 37,588 (5,849 total cases)
--- 24.3% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 450 (70 total deaths)
--- 42.4% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 41.9% (6,523 fully vaccinated)
#3. Menard County, IL
- Cumulative cases per 100k: 35,093 (4,280 total cases)
--- 16.0% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 205 (25 total deaths)
--- 35.1% less deaths per 100k residents than Illinois
- Population that is fully vaccinated: 58.3% (7,108 fully vaccinated)
#2. Hardin County, IL
- Cumulative cases per 100k: 35,567 (1,359 total cases)
--- 17.6% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 523 (20 total deaths)
--- 65.5% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 44.2% (1,688 fully vaccinated)
#1. Hamilton County, IL
- Cumulative cases per 100k: 31,395 (2,548 total cases)
--- 3.8% more cases per 100k residents than Illinois
- Cumulative deaths per 100k: 394 (32 total deaths)
--- 24.7% more deaths per 100k residents than Illinois
- Population that is fully vaccinated: 40.5% (3,286 fully vaccinated)