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1 / 51#51. Mississippi
- Peak flu vaccination coverage, 2021-2022 season: 38.2%
- 13.2% points lower than the national rate

Your yearly flu vaccine protects you and those around you from the influenza virus, which could be deadly. Getting vaccinated too early could mean you may have reduced immunity by the time the flu virus circulates in your community. The Centers for Disease Control and Prevention recommends getting a flu vaccine in September or October to prepare for the flu season in the late fall and winter.
Flu vaccines are updated yearly to protect against the viruses in circulation for the upcoming flu season. Vaccines are readily available through places such as health departments, community clinics, and pharmacies. It takes about two weeks after vaccination to produce enough antibodies to the virus to fully protect you against the flu.
Rates of the flu have dropped dramatically in the last couple of years, mainly due to measures taken to reduce the spread of COVID-19: mask-wearing, social distancing, and reduced travel. However, experts warn of a potential resurgence of the flu in 2022 since many pandemic-related restrictions have dropped.
Most people over 6 months old can get a flu vaccine, including pregnant women and those with egg allergies. Flu vaccines are administered either as an intramuscular injection, usually in the upper arm, or as a nasal spray. Vaccines can protect against three strains of the flu virus (trivalent vaccines) or four strains of the virus (quadrivalent vaccines).
The most common side effects of the injectable flu vaccine are soreness at the injection site, muscle aches, and a fever. The side effects of the nasal spray vaccine are the same but may also include a runny nose.
People over 65 should get one of two vaccines: A high-dose quadrivalent vaccine, which contains four times the flu antigen of the standard vaccine (the flu antigen prompts the body's immune response), or an adjuvanted vaccine, which encourages a more robust immune response. In the U.S., both vaccines are approved solely for those over 65.
According to the CDC, the flu vaccine is safe to administer at the same time as the COVID-19 vaccine or booster shot. While this may increase the likelihood of experiencing side effects like fatigue or muscle aches, some might opt to get both vaccines simultaneously for convenience.
To determine the peak seasonal flu vaccination rate for every state, Stacker consulted the CDC's Influenza Seasons Vaccination Coverage Report. Data on flu vaccination coverage for children 6 months to 17 years is based on CDC's National Immunization Survey-Flu, and coverage for adults is based on CDC survey data. States are ranked by their peak vaccination coverage for the most recent flu season, with most data collection finishing in May or June of 2022.
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Sean Pavone // Shutterstock
1 / 51- Peak flu vaccination coverage, 2021-2022 season: 38.2%
- 13.2% points lower than the national rate
Mark Winfrey // Shutterstock
2 / 51- Peak flu vaccination coverage, 2021-2022 season: 41.2%
- 10.2% points lower than the national rate
Khairil Azhar Junos // Shutterstock
3 / 51- Peak flu vaccination coverage, 2021-2022 season: 42.0%
- 9.4% points lower than the national rate
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4 / 51- Peak flu vaccination coverage, 2021-2022 season: 42.3%
- 9.1% points lower than the national rate
Impact Photography // Shutterstock
5 / 51- Peak flu vaccination coverage, 2021-2022 season: 42.3%
- 9.1% points lower than the national rate
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Juice Flair // Shutterstock
6 / 51- Peak flu vaccination coverage, 2021-2022 season: 42.9%
- 8.5% points lower than the national rate
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7 / 51- Peak flu vaccination coverage, 2021-2022 season: 43.1%
- 8.3% points lower than the national rate
Sean Pavone // Shutterstock
8 / 51- Peak flu vaccination coverage, 2021-2022 season: 44.1%
- 7.3% points lower than the national rate
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9 / 51- Peak flu vaccination coverage, 2021-2022 season: 46.3%
- 5.1% points lower than the national rate
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10 / 51- Peak flu vaccination coverage, 2021-2022 season: 46.5%
- 4.9% points lower than the national rate
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11 / 51- Peak flu vaccination coverage, 2021-2022 season: 46.6%
- 4.8% points lower than the national rate
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12 / 51- Peak flu vaccination coverage, 2021-2022 season: 47.0%
- 4.4% points lower than the national rate
PanyaStudio // Shutterstock
13 / 51- Peak flu vaccination coverage, 2021-2022 season: 47.1%
- 4.3% points lower than the national rate
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14 / 51- Peak flu vaccination coverage, 2021-2022 season: 47.8%
- 3.6% points lower than the national rate
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15 / 51- Peak flu vaccination coverage, 2021-2022 season: 47.8%
- 3.6% points lower than the national rate
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Matt Gush // Shutterstock
16 / 51- Peak flu vaccination coverage, 2021-2022 season: 48.1%
- 3.3% points lower than the national rate
f11photo // Shutterstock
17 / 51- Peak flu vaccination coverage, 2021-2022 season: 48.5%
- 2.9% points lower than the national rate
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18 / 51- Peak flu vaccination coverage, 2021-2022 season: 49.0%
- 2.4% points lower than the national rate
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19 / 51- Peak flu vaccination coverage, 2021-2022 season: 49.6%
- 1.8% points lower than the national rate
MedStockPhotos // Shutterstock
20 / 51- Peak flu vaccination coverage, 2021-2022 season: 49.8%
- 1.6% points lower than the national rate
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Jacob Boomsma // Shutterstock
21 / 51- Peak flu vaccination coverage, 2021-2022 season: 49.8%
- 1.6% points lower than the national rate
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22 / 51- Peak flu vaccination coverage, 2021-2022 season: 49.9%
- 1.5% points lower than the national rate
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23 / 51- Peak flu vaccination coverage, 2021-2022 season: 50.3%
- 1.1% points lower than the national rate
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24 / 51- Peak flu vaccination coverage, 2021-2022 season: 50.4%
- 1.0% points lower than the national rate
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25 / 51- Peak flu vaccination coverage, 2021-2022 season: 50.6%
- 0.8% points lower than the national rate
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Jacob Boomsma // Shutterstock
26 / 51- Peak flu vaccination coverage, 2021-2022 season: 51.7%
- 0.3% points higher than the national rate
Sean Pavone // Shutterstock
27 / 51- Peak flu vaccination coverage, 2021-2022 season: 51.9%
- 0.5% points higher than the national rate
Jacob Boomsma // Shutterstock
28 / 51- Peak flu vaccination coverage, 2021-2022 season: 52.6%
- 1.2% points higher than the national rate
APN Photography // Shutterstock
29 / 51- Peak flu vaccination coverage, 2021-2022 season: 52.9%
- 1.5% points higher than the national rate
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30 / 51- Peak flu vaccination coverage, 2021-2022 season: 53.3%
- 1.9% points higher than the national rate
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Khairil Azhar Junos // Shutterstock
31 / 51- Peak flu vaccination coverage, 2021-2022 season: 53.4%
- 2.0% points higher than the national rate
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32 / 51- Peak flu vaccination coverage, 2021-2022 season: 54.4%
- 3.0% points higher than the national rate
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33 / 51- Peak flu vaccination coverage, 2021-2022 season: 54.5%
- 3.1% points higher than the national rate
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34 / 51- Peak flu vaccination coverage, 2021-2022 season: 54.6%
- 3.2% points higher than the national rate
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35 / 51- Peak flu vaccination coverage, 2021-2022 season: 55.1%
- 3.7% points higher than the national rate
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36 / 51- Peak flu vaccination coverage, 2021-2022 season: 55.1%
- 3.7% points higher than the national rate
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37 / 51- Peak flu vaccination coverage, 2021-2022 season: 55.3%
- 3.9% points higher than the national rate
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38 / 51- Peak flu vaccination coverage, 2021-2022 season: 55.6%
- 4.2% points higher than the national rate
Sean Pavone // Shutterstock
39 / 51- Peak flu vaccination coverage, 2021-2022 season: 55.7%
- 4.3% points higher than the national rate
Real Window Creative // Shutterstock
40 / 51- Peak flu vaccination coverage, 2021-2022 season: 55.9%
- 4.5% points higher than the national rate
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Jacob Boomsma // Shutterstock
41 / 51- Peak flu vaccination coverage, 2021-2022 season: 57.5%
- 6.1% points higher than the national rate
Ken Wolter // Shutterstock
42 / 51- Peak flu vaccination coverage, 2021-2022 season: 57.7%
- 6.3% points higher than the national rate
PhotoItaliaStudio // Shutterstock
43 / 51- Peak flu vaccination coverage, 2021-2022 season: 58.5%
- 7.1% points higher than the national rate
Sean Pavone // Shutterstock
44 / 51- Peak flu vaccination coverage, 2021-2022 season: 59.3%
- 7.9% points higher than the national rate
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45 / 51- Peak flu vaccination coverage, 2021-2022 season: 60.9%
- 9.5% points higher than the national rate
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Real Window Creative // Shutterstock
46 / 51- Peak flu vaccination coverage, 2021-2022 season: 61.9%
- 10.5% points higher than the national rate
Sean Pavone // Shutterstock
47 / 51- Peak flu vaccination coverage, 2021-2022 season: 62.1%
- 10.7% points higher than the national rate
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48 / 51- Peak flu vaccination coverage, 2021-2022 season: 62.9%
- 11.5% points higher than the national rate
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49 / 51- Peak flu vaccination coverage, 2021-2022 season: 63.0%
- 11.6% points higher than the national rate
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50 / 51- Peak flu vaccination coverage, 2021-2022 season: 63.7%
- 12.3% points higher than the national rate
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Tupungato // Shutterstock
51 / 51- Peak flu vaccination coverage, 2021-2022 season: 66.1%
- 14.7% points higher than the national rate